EC Number   |
Title |
Organism |
|---|
   3.4.21.46 | Complement factor D homolog involved in the alternative complement pathway of rock bream (Oplegnathus fasciatus) Molecular and functional characterization and immune responsive mRNA expression analysis |
Oplegnathus fasciatus |
| 3.4.21.46 | Complement factor D protects mice from ethanol-induced inflammation and liver injury |
Mus musculus |
| 3.4.21.46 | Design, synthesis, and preclinical characterization of selective factor D inhibitors targeting the alternative complement pathway |
Homo sapiens |
| 3.4.21.46 | Discovery and design of first benzylamine-based ligands binding to an unlocked conformation of the complement factor D |
Homo sapiens |
| 3.4.21.46 | Discovery of highly potent and selective small-molecule reversible factor D inhibitors demonstrating alternative complement pathway inhibition in vivo |
Homo sapiens |
| 3.4.21.46 | Dynamic regulation of platelet-derived growth factor D (PDGF-D) activity and extracellular spatial distribution by matriptase-mediated proteolysis |
Homo sapiens |
| 3.4.21.46 | Molecular characterization, expression and antimicrobial activity of complement factor D in Megalobrama amblycephala |
Megalobrama amblycephala |
| 3.4.21.46 | Senescent dermal fibroblasts negatively influence fibroblast extracellular matrix-related gene expression partly via secretion of complement factor D |
Homo sapiens |
| 3.4.21.46 | Small molecule-induced complement factor D (adipsin) promotes lipid accumulation and adipocyte differentiation |
Mus musculus |
| 3.4.21.46 | Alternative complement pathway component Factor D contributes to efficient clearance of tissue debris following acute CCl4-induced injury |
Mus musculus |
