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Literature summary for 3.4.21.35 extracted from

  • El Moujahed, A.; Brillard-Bourdet, M.; Juliano, M.A.; Moreau, T.; Chagas, J.R.; Gutman, N.; Prado, E.S.; Gauthier, F.
    Kininogen-derived fluorogenic substrates for investigating the vasoactive properties of rat kallikreins. Identification of a T-kinin-releasing rat kallikrein (1997), Eur. J. Biochem., 247, 652-658.
    View publication on PubMed
Search for more literature for 3.4.21.35

Inhibitors

Inhibitors Comment Organism Structure
o-aminobenzoyl-TSVIRRPQ-ethylenediamine
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.005
-
 2-aminobenzoyl-TSVIRRVQ-ethylenediamine
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular secretion Homo sapiens
-
-
extracellular secretion Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
polypeptide + H2O Homo sapiens
-
 peptides
-
 ?
polypeptide + H2O Rattus norvegicus
-
 peptides
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
from urine Homo sapiens
to homogeneity Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
urine
-
 Homo sapiens
-
urine
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Homo sapiens
additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-aminobenzoyl-TSVIRRVQ-ethylenediamine + H2O
-
 Homo sapiens ?
-
 ?
o-aminobenzoyl-FRAPR-N-(2,4-dinitrophenyl)ethylene diamine + H2O
-
 Homo sapiens ?
-
 ?
o-aminobenzoyl-FRAPR-N-(2,4-dinitrophenyl)ethylene diamine + H2O
-
 Rattus norvegicus ?
-
 ?
o-aminobenzoyl-FRLVR-N-(2,4-dinitrophenyl)ethylene diamine + H2O
-
 Homo sapiens ?
-
 ?
o-aminobenzoyl-FRLVR-N-(2,4-dinitrophenyl)ethylene diamine + H2O
-
 Rattus norvegicus ?
-
 ?
o-aminobenzoyl-LMKRP-N-(2,4-dinitrophenyl)ethylene diamine + H2O
-
 Homo sapiens o-aminobenzoyl-LM + KRP-N-(2,4-dinitrophenyl)ethylene diamine
-
 ?
o-aminobenzoyl-SVIRRVQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O
-
 Homo sapiens ?
-
 ?
o-aminobenzoyl-SVIRRVQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O
-
 Rattus norvegicus ?
-
 ?
o-aminobenzoyl-TSVIRRPQ-N-(2,4-dinitrophenyl)ethylene diamine + H2O
-
 Rattus norvegicus ?
-
 ?
polypeptide + H2O
-
 Homo sapiens peptides
-
 ?
polypeptide + H2O
-
 Rattus norvegicus peptides
-
 ?
Pro-Phe-Arg-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens Pro-Phe-Arg + 7-amino-4-methylcoumarin
-
 ?
Pro-Phe-Arg-7-amido-4-methylcoumarin + H2O
-
 Rattus norvegicus Pro-Phe-Arg + 7-amino-4-methylcoumarin
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0042
-
 o-aminobenzoyl-TSVIRRPQ-ethylenediamine pH 9.0, 37°C Homo sapiens