Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NaCl | 1 M, shift in oligomeric state of the protein from dimer towards monomer | Plasmodium berghei |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
2.11 | - |
Glycerol 2-phosphate | pH 7.4, 37°C | Plasmodium berghei | |
2.5 | 3 | 2-Phosphoglycolate | pH 7.4, 37°C | Plasmodium berghei | |
4.77 | - |
2-phospho-L-lactate | pH 7.4, 37°C | Plasmodium berghei |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | preferred divalent cation | Plasmodium berghei | |
additional information | divalent cation required | Plasmodium berghei |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
78000 | - |
gel filtration | Plasmodium berghei |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium berghei | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-phospho-L-lactate + H2O | - |
Plasmodium berghei | L-lactate + phosphate | - |
? | |
2-Phosphoglycolate + H2O | - |
Plasmodium berghei | Glycolate + phosphate | - |
? | |
4-nitrophenyl phosphate + H2O | - |
Plasmodium berghei | 4-nitrophenol + phosphate | - |
? | |
glycerol 2-phosphate + H2O | - |
Plasmodium berghei | glycerol + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 37000, calculated from sequence | Plasmodium berghei |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
10.18 | - |
Glycerol 2-phosphate | pH 7.4, 37°C | Plasmodium berghei | |
67.34 | - |
2-phospho-L-lactate | pH 7.4, 37°C | Plasmodium berghei | |
75.15 | - |
2-Phosphoglycolate | pH 7.4, 37°C | Plasmodium berghei |
General Information | Comment | Organism |
---|---|---|
physiological function | protein is essential for parasite survival during asexual stages | Plasmodium berghei |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
4.83 | - |
Glycerol 2-phosphate | pH 7.4, 37°C | Plasmodium berghei | |
14.11 | - |
2-phospho-L-lactate | pH 7.4, 37°C | Plasmodium berghei | |
29.75 | - |
2-Phosphoglycolate | pH 7.4, 37°C | Plasmodium berghei |