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1,3-dihydroxyacetone phosphate + H2O
1,3-dihydroxyacetone + phosphate
-
about 20% of the activity with 2-phosphoglycolate
-
-
?
2-Chloroethyl-phosphate + H2O
Chloroethanol + phosphate
-
-
-
-
?
2-glycerol phosphate + H2O
glycerol + phosphate
-
about 17% of the activity with 2-phosphoglycolate
-
-
?
2-Hydroxyethyl-phosphate + H2O
Hydroxyethanol + phosphate
-
-
-
-
?
2-phospho-L-lactate + H2O
L-lactate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
D-fructose-1,6-bisphosphate + H2O
D-fructose-1-phosphate + phosphate
-
-
?
D-ribulose-5-phosphate + H2O
D-ribulose + phosphate
-
-
?
diphosphate + H2O
2 phosphate
-
-
?
Ethyl-phosphate + H2O
Ethanol + phosphate
glyceraldehyde-3-phosphate + H2O
glyceraldehyde + phosphate
-
about 20% of the activity with 2-phosphoglycolate
-
-
?
glycerol 1-phosphate + H2O
glycerol + phosphate
-
-
-
?
glycerol 2-phosphate + H2O
glycerol + phosphate
i-Propyl-phosphate + H2O
i-Propanol + phosphate
-
slowly
-
-
?
L-Phospholactate + H2O
L-Lactate + phosphate
-
-
-
-
?
Methyl-phosphate + H2O
Methanol + phosphate
-
-
-
-
?
n-Propyl-phosphate + H2O
n-Propanol + phosphate
-
weak
-
-
?
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
phosphoglycolate + H2O
glycolate + phosphate
additional information
?
-
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
a key enzyme of photorespiration in photosynthetic organisms
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
the enzyme is involved in a reaction relevant for DNA repair
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
first unique step of oxidative photosynthetic carbon cycle
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
first unique step of oxidative photosynthetic carbon cycle
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
2-Phosphoglycolate + H2O
Glycolate + phosphate
-
-
-
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
-
-
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
-
-
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
-
-
?
4-nitrophenyl phosphate + H2O
4-nitrophenol + phosphate
-
-
-
-
?
Ethyl-phosphate + H2O
Ethanol + phosphate
-
-
-
-
?
Ethyl-phosphate + H2O
Ethanol + phosphate
-
-
-
-
?
Ethyl-phosphate + H2O
Ethanol + phosphate
-
-
-
-
?
glycerol 2-phosphate + H2O
glycerol + phosphate
-
-
-
-
?
glycerol 2-phosphate + H2O
glycerol + phosphate
-
-
-
?
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
-
-
-
?
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
-
-
?
phosphoglycolate + H2O
glycolate + phosphate
-
-
-
-
?
phosphoglycolate + H2O
glycolate + phosphate
-
-
-
-
?
phosphoglycolate + H2O
glycolate + phosphate
-
-
-
?
phosphoglycolate + H2O
glycolate + phosphate
-
-
-
?
additional information
?
-
-
no substrates: phosphopeptides, 4-nitrophenylsulfate
-
-
?
additional information
?
-
-
no substrates: phosphopeptides, 4-nitrophenylsulfate
-
-
?
additional information
?
-
not: 3-phosphoglycerate, D-ribose-5-phosphate, phosphoenolpyruvate, O-phospho-1-serine, p-nitrophenylphosphate
-
?
additional information
?
-
-
not: 3-phosphoglycerate, D-ribose-5-phosphate, phosphoenolpyruvate, O-phospho-1-serine, p-nitrophenylphosphate
-
?
additional information
?
-
-
-
-
-
?
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K+
-
needed for optimal activation, can be replaced by Li+, Na+, Rb+, Cs+, NH4+
KCl
activates at chloride ion concentration up to 50 mM
ZnCl2
-
slight activation up to 0.1 mM
Cl-
the activity is 11fold increased, cooperative effect of Cl- and Mg2+
Cl-
activates at low concentration, below 50
Co2+
-
cations tested, in decreasing order of efficiency: Mn2+, Co2+, Mg2+, Ni2+
Co2+
-
cations tested, in decreasing order of efficiency: Mn2+, Co2+, Mg2+, Ni2+
Co2+
-
Anacystis: no activation, Chlamydomonas: activation
Co2+
-
Chlamydomonas: most effective activator
Co2+
-
Anacystis: no activation, Chlamydomonas: activation
Co2+
activates, KD = 0.036 +/- 0.004
Mg2+
-
cations tested, in decreasing order of efficiency: Mn2+, Co2+, Mg2+, Ni2+
Mg2+
-
cations tested, in decreasing order of efficiency: Mn2+, Co2+, Mg2+, Ni2+
Mg2+
cooperative effect of Cl- and Mg2+
Mg2+
-
most effective activator
Mg2+
-
preferred divalent cation
Mg2+
activates, KD = 0.13 +/- 0.01
Mg2+
-
most effective activator
Mn2+
-
cations tested, in decreasing order of efficiency: Mn2+, Co2+, Mg2+, Ni2+
Mn2+
-
cations tested, in decreasing order of efficiency: Mn2+, Co2+, Mg2+, Ni2+
Mn2+
activates, KD = 0.02 +/- 0.004
Ni2+
-
cations tested, in decreasing order of efficiency: Mn2+, Co2+, Mg2+, Ni2+
Ni2+
-
cations tested, in decreasing order of efficiency: Mn2+, Co2+, Mg2+, Ni2+
Zn2+
-
Anacystis: no activation, Chlamydomonas: activation
Zn2+
-
Anacystis: no activation, Chlamydomonas: activation
Zn2+
-
activates less than Mg2+
additional information
-
divalent cation required, no cofactor: Cu2+
additional information
-
divalent cation required, no cofactor: Cu2+
additional information
-
divalent cation required
additional information
-
univalent cation required for optimum activity
additional information
-
divalent cation required
additional information
-
divalent cation required
additional information
-
divalent cation required
additional information
-
divalent cation required
additional information
-
divalent cation required
additional information
-
divalent cation required
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Baldy, P.; Piquemal, M.; Cavalie, G.
Phosphoglycolate phosphatase: immunological comparisons of the enzyme from the different photosynthetic groups of plants using maize polyclonal antiserum
Plant Sci.
60
9-20
1989
Amaranthus caudatus, Glycine max, Hordeum vulgare, Megathyrsus maximus, More, Panicum miliaceum, Panicum milioides, Sorghum bicolor, Triticum aestivum, Zea mays
-
brenda
Huh, D.H.; Kursell, A.V.; Husic, H.D.
Kinetic properties of phosphoglycolate phosphatase from Pisum sativum and Phaseolus vulgaris
Phytochemistry
28
719-720
1989
Pisum sativum
-
brenda
Rose, Z.B.; Grove, D.S.; Seal, S.N.
Mechanism of activation by anions of phosphoglycolate phosphatases from spinach and human red blood cells
J. Biol. Chem.
261
10996-11002
1986
Homo sapiens, Spinacia oleracea
brenda
Hardy, P.; Baldy, P.
Corn phosphoglycolate phosphatase: purification and properties
Planta
168
245-252
1986
Zea mays
brenda
Husic, H.D.; Tolbert, N.E.
Properties of phosphoglycolate phosphatase from Chlamydomonas reinhardtii and Anacystis nidulans
Plant Physiol.
79
394-399
1985
Trichormus variabilis, Synechococcus elongatus PCC 7942 = FACHB-805, Chlamydomonas reinhardtii, Chlorella vulgaris
brenda
Husic, H.D.; Tolbert, N.E.
Anion and divalent cation activation of phosphoglycolate phosphatase from leaves
Arch. Biochem. Biophys.
229
64-72
1984
Spinacia oleracea
brenda
Rose, Z.B.
Phosphoglycolate phosphatase from human red blood cells
Arch. Biochem. Biophys.
208
602-609
1981
Homo sapiens
brenda
Zecher, R.; Wolf, H.U.
Partial purification and characterization of human erythrocyte phosphoglycollate phosphatase
Biochem. J.
191
117-124
1980
Homo sapiens
brenda
Verin-Vergeau, C.; Baldy, P.; Cavalie, G.
Phosphoglycolate phosphatases from French bean leaves: catalytic properties of two isoenzymes
Phytochemistry
19
763-767
1980
Phaseolus vulgaris
-
brenda
Verin-Vergeau, C.; Baldy, P.; Cavalie, G.
Phosphoglycolate phosphatase from haricot leaves: two isofunctional forms
Phytochemistry
18
1279-1282
1979
Phaseolus vulgaris
-
brenda
Badwey, J.A.
Phosphoglycolate phosphatase in human erythrocytes
J. Biol. Chem.
252
2441-2443
1977
Homo sapiens
brenda
Kerr, M.W.; Gear, C.F.
Phosphoglycolate phosphatase isolated from pea leaves
Biochem. Soc. Trans.
2
338-340
1974
Pisum sativum
-
brenda
Beutler, E.; West, C.
An improved assay and some properties of phosphoglycolate phosphatase
Anal. Biochem.
106
163-168
1980
Rattus norvegicus
brenda
Christeller, J.T.; Tolbert, N.E.
Phosphoglycolate phosphatase. Purification and properties
J. Biol. Chem.
253
1780-1785
1978
Nicotiana tabacum
brenda
Christeller, J.T.; Tolbert, N.E.
Mechanism of phosphoglycolate phosphatase. Studies of hydrolysis and transphosphorylation, substrate analogs, and sulfhydryl inhibition
J. Biol. Chem.
253
1791-1798
1978
Nicotiana tabacum
brenda
Christeller, J.T.; Tolbert, N.E.
Phosphoglycolate phosphatase. Effect of cation and pH on activity
J. Biol. Chem.
253
1786-1790
1978
Nicotiana tabacum
brenda
Richardson, K.E.; Tolbert, N.E.
Phosphoglycolic acid phosphatase
J. Biol. Chem.
236
1285-1290
1961
Nicotiana tabacum
brenda
Pellicer, M.T.; Nunez, M.F.; Aguilar, J.; Badia, J.; Baldoma, L.
Role of 2-phosphoglycolate phosphatase of Escherichia coli in metabolism of the 2-phosphoglycolate formed in DNA repair
J. Bacteriol.
185
5815-5821
2003
Agrobacterium tumefaciens, Cupriavidus necator, Escherichia coli, Escherichia coli (P32662), Salmonella enterica, Haemophilus influenzae, Shigella flexneri, Klebsiella aerogenes (Q9EYY5)
brenda
Mamedov, T.G.; Suzuki, K.; Miura, K.; Kucho Ki, K.; Fukuzawa, H.
Characteristics and sequence of phosphoglycolate phosphatase from a eukaryotic green alga Chlamydomonas reinhardtii
J. Biol. Chem.
276
45573-45579
2001
Triticum aestivum, Aquifex aeolicus (O67359), Escherichia coli (P32662), Cupriavidus necator (P40852), Synechocystis sp. (P73525), Chlamydomonas reinhardtii (Q948T5), Chlamydomonas reinhardtii
brenda
Kim, Y.; Yakunin, A.F.; Kuznetsova, E.; Xu, X.; Pennycooke, M.; Gu, J.; Cheung, F.; Proudfoot, M.; Arrowsmith, C.H.; Joachimiak, A.; Edwards, A.M.; Christendat, D.
Structure- and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum
J. Biol. Chem.
279
517-526
2004
Homo sapiens, Spinacia oleracea, Thermoplasma acidophilum (Q9HLQ2), Thermoplasma acidophilum
brenda
Garbayo, I.; Forja, E.; Salguero, A.; Cuaresma, M.; Vegaz, J.M.; Ichez, C.V.
Enhancement of photorespiration in immobilized Chlamydomonas reinhardtii cells
Biotechnol. Lett.
27
265-267
2005
Chlamydomonas reinhardtii, Chlamydomonas reinhardtii 21
brenda
Proudfoot, M.
corresponding Author: Dr. Alexander Yakunin, C.H. Best Institute, 112 College St. Room 72, Toronto On M5G 1L6, Canada
Private Communication
10
1-1
2007
Saccharomyces cerevisiae (P19881)
-
brenda
Schwarte, S.; Bauwe, H.
Identification of the photorespiratory 2-phosphoglycolate phosphatase, PGLP1, in Arabidopsis
Plant Physiol.
144
1580-1586
2007
Arabidopsis thaliana
brenda
Liu, H.; Zhou, H.; Zhu, D.; Bi, R.
Overexpression, purification, characterization and preliminary crystallographic study of phosphoglycolate phosphatase from Shigella flexneri 2a strain 301
Acta Crystallogr. Sect. F
F65
29-33
2009
Shigella flexneri (Q83PX1), Shigella flexneri
brenda
Park, M.; Kim, M.S.; Lee, K.M.; Hwang, S.Y.; Ahn, T.I.
Characterization of a cryptic plasmid from an alpha-proteobacterial endosymbiont of Amoeba proteus
Plasmid
61
78-87
2009
alpha proteobacterium endosymbiont of Amoeba proteus (B3VBH3)
brenda
Segerer, G.; Engelmann, D.; Kaestner, A.; Troetzmueller, M.; Koefeler, H.; Stigloher, C.; Thiele, C.; Jeanclos, E.; Gohla, A.
A phosphoglycolate phosphatase/AUM-dependent link between triacylglycerol turnover and epidermal growth factor signaling
Biochim. Biophys. Acta
1863
584-594
2018
Mus musculus (Q8CHP8)
brenda
Krocova, E.; Neradova, S.; Kupcik, R.; Janovska, S.; Bilkova, Z.; Heidingsfeld, O.
PHO15 genes of Candida albicans and Candida parapsilosis encode HAD-type phosphatases dephosphorylating 2-phosphoglycolate
FEMS Yeast Res.
19
foy112
2019
Candida albicans, Candida parapsilosis
brenda
Seifried, A.; Bergeron, A.; Boivin, B.; Gohla, A.
Reversible oxidation controls the activity and oligomeric state of the mammalian phosphoglycolate phosphatase AUM
Free Radic. Biol. Med.
97
75-84
2016
Mus musculus (Q8CHP8), Mus musculus
brenda
Rai, S.; Lucius, S.; Kern, R.; Bauwe, H.; Kaplan, A.; Kopka, J.; Hagemann, M.
The Synechocystis sp. PCC 6803 genome encodes up to four 2-phosphoglycolate phosphatases
Front. Plant Sci.
9
1718
2018
Synechocystis sp. PCC 6803 (P74697)
brenda
Nagappa, L.K.; Satha, P.; Govindaraju, T.; Balaram, H.
Phosphoglycolate phosphatase is a metabolic proof-reading enzyme essential for cellular function in Plasmodium berghei
J. Biol. Chem.
294
4997-5007
2019
Plasmodium berghei
brenda
Levey, M.; Timm, S.; Mettler-Altmann, T.; Luca Borghi, G.; Koczor, M.; Arrivault, S.; Pm Weber, A.; Bauwe, H.; Gowik, U.; Westhoff, P.
Efficient 2-phosphoglycolate degradation is required to maintain carbon assimilation and allocation in the C4 plant Flaveria bidentis
J. Exp. Bot.
70
575-587
2019
Flaveria bidentis
brenda
Segerer, G.; Hadamek, K.; Zundler, M.; Fekete, A.; Seifried, A.; Mueller, M.J.; Koentgen, F.; Gessler, M.; Jeanclos, E.; Gohla, A.
An essential developmental function for murine phosphoglycolate phosphatase in safeguarding cell proliferation
Sci. Rep.
6
35160
2016
Mus musculus (Q8CHP8), Mus musculus
brenda