Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.1.77 extracted from

  • Munford, R.S.; Erwin, A.L.
    Eukaryotic lipopolysaccharide deacylation enzyme (1992), Methods Enzymol., 209, 485-492.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
Triton X-100 required Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
in BHK 570 cells Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ 5 mM enhances activity by 30-50% at low substrate concentration, inhibitory at high substrate concentration Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-(acyloxy)acyl group of bacterial toxin Homo sapiens detoxification of LPS 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.000005
-
cell lysate Homo sapiens
1.555
-
purified enzyme Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-(acyloxy)acyl group of bacterial toxin + H2O
-
Homo sapiens 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
?
3-(acyloxy)acyl group of bacterial toxin detoxification of LPS Homo sapiens 3-hydroxyacyl group of bacterial toxin + a fatty acid
-
?