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Literature summary for 3.1.1.64 extracted from
- Rpe65 is a retinyl ester binding protein that presents insoluble substrate to the isomerase in retinal pigment epithelial cells (2004), J. Biol. Chem., 279, 635-643.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | enzyme activity is dependent upon the presence of Rpe65 | Mus musculus |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in baculovirus-infected Sf9 cells | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Mus musculus | 16020 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| retinal pigment epithelial cell | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| all-trans-retinyl palmitate + H2O | - |
Mus musculus | 11-cis-retinol + palmitate | - |
? |  |
| additional information | Rpe65 presents retinyl esters as substrate to the isomerase for synthesis of visual chromophore | Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| IMH | - |
Mus musculus |
| isomerohydrolase | - |
Mus musculus |
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Release 2023.1 (January 2023)
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