Activating Compound | Comment | Organism | Structure |
---|---|---|---|
8-bromo-cGMP | - |
Rattus norvegicus | |
cGMP | - |
Rattus norvegicus | |
formyl-methionyl-leucyl-phenylalanine | - |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
KT5823 | in vivo inhibition in leukemia cells causes reduced agonist-stimulated beta-hexosaminidase release and abolishes vesicular fusion with the plasma membrane | Rattus norvegicus | |
Rp-8-Br-cGMP | in vivo inhibition in leukemia cells causes reduced agonist-stimulated beta-hexosaminidase release and abolishes vesicular fusion with the plasma membrane | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + target membrane SNARe complex | Rattus norvegicus | the enzyme is involved in regulation of degranulation of leukocytes by phosphorylation of target membrane SNARe complex together with the phosphoinositide 3-kinase | ADP + phosphorylated target membrane SNARe complex | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leukemia cell | - |
Rattus norvegicus | - |
leukocyte | - |
Rattus norvegicus | - |
mast cell | - |
Rattus norvegicus | - |
RBL-2H3 cell | a basophilic leukemia cell line | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + target membrane SNARe complex | the enzyme is involved in regulation of degranulation of leukocytes by phosphorylation of target membrane SNARe complex together with the phosphoinositide 3-kinase | Rattus norvegicus | ADP + phosphorylated target membrane SNARe complex | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PKG | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Rattus norvegicus |