Activating Compound | Comment | Organism | Structure |
---|---|---|---|
5-fluorouracil | - |
Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | a potential mechanism of action of Src kinase inhibitors on 5-fluorouracil chemosensitivity may be linked to the inhibition of 5-fluorouracil-induced EGFR-AKT activation | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine | PP2, combination of 5-fluorouracil-PP2 decreases the 5-fluorouracil-induced activation of EGFR-AKT pathway | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
AsPC-1 cell | - |
Homo sapiens | - |
L3.6pl cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
Egfr | - |
Homo sapiens |
epidermal growth factor receptor | - |
Homo sapiens |