Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | 2 mM, 25% inhibition | Sus scrofa | |
AMP | 2 mM, 7% inhibition | Sus scrofa | |
ATP | 2 mM, 82% inhibition; inhibition is removed by raising Mg2+ concentrations | Sus scrofa | |
CDP | 2 mM, 20% inhibition | Sus scrofa | |
CTP | 2 mM, 77% inhibition | Sus scrofa | |
dipicolinic acid | 1 mM, 24% inhibition | Sus scrofa | |
dithiobis(2-nitrobenzoic acid) | 10 mM, 88.7% inhibition | Sus scrofa | |
GDP | 2 mM, 29% inhibition | Sus scrofa | |
GTP | 2 mM, 77% inhibition | Sus scrofa | |
IDP | 2 mM, 29% inhibition | Sus scrofa | |
IMP | 2 mM, 6% inhibition | Sus scrofa | |
isocinchomeric acid | 1 mM, 15% inhibition | Sus scrofa | |
ITP | 2 mM, 81% inhibition | Sus scrofa | |
lutidinic acid | 1 mM, 17% inhibition | Sus scrofa | |
Monoiodoacetic acid | 50 mM, 99.8% inhibition | Sus scrofa | |
NEM | 5 mM, 86% inhibition | Sus scrofa | |
PCMB | 0.05 mM, complete inhibition | Sus scrofa | |
Phthalic acid | competitive to quinolinate | Sus scrofa | |
UDP | 2 mM, 32% inhibition | Sus scrofa | |
UTP | 2 mM, 74% inhibition | Sus scrofa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | absolute requirement. Optimal concentration is 1 mM in absence of ATP and 7 mM in presence of ATP at 5 mM | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Sus scrofa | intermediary enzyme in the de novo NAD biosynthetic pathway | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | intermediary enzyme in the de novo NAD biosynthetic pathway | Sus scrofa | ? | - |
? | |
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate | - |
Sus scrofa | nicotinate D-ribonucleotide + diphosphate + CO2 | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.17 | - |
Phthalic acid | - |
Sus scrofa |