Inhibitors | Comment | Organism | Structure |
---|---|---|---|
acetyl-CoA | - |
Thermus thermophilus | |
L-Lys | - |
Thermus thermophilus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.028 | - |
acetyl-CoA | - |
Thermus thermophilus | |
0.032 | - |
acetyl-CoA | - |
Thermus thermophilus | |
0.044 | - |
2-oxoglutarate | - |
Thermus thermophilus | |
0.255 | - |
oxaloacetate | - |
Thermus thermophilus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
60000 | - |
gel filtration | Thermus thermophilus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + H2O + 2-oxoglutarate | Thermus thermophilus | first enzyme of the lysine biosynthetic pathway | 2-hydroxybutane-1,2,4-tricarboxylate + CoA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermus thermophilus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Thermus thermophilus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + H2O + 2-oxoglutarate | - |
Thermus thermophilus | 2-hydroxybutane-1,2,4-tricarboxylate + CoA | - |
? | |
acetyl-CoA + H2O + 2-oxoglutarate | first enzyme of the lysine biosynthetic pathway | Thermus thermophilus | 2-hydroxybutane-1,2,4-tricarboxylate + CoA | - |
? | |
acetyl-CoA + H2O + oxaloacetate | - |
Thermus thermophilus | 2-hydroxypropane-1,2,3-tricarboxylate + CoA | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
60 | - |
- |
Thermus thermophilus |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
40 | 80 | 40°C: about 70% of maximal activity, 80°C: about 60% of maximal activity | Thermus thermophilus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
70 | - |
rapid loss of activity above | Thermus thermophilus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.967 | - |
acetyl-CoA | - |
Thermus thermophilus | |
0.967 | - |
oxaloacetate | - |
Thermus thermophilus | |
1.53 | - |
acetyl-CoA | reaction with 2-oxoglutarate | Thermus thermophilus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0094 | - |
L-Lys | - |
Thermus thermophilus |