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show all sequences of 2.3.1.47

Distribution of 7-keto-8-aminopelargonic acid synthetase in bacteria and the control mechanism of the enzyme activity

Izumi, Y.; Sato, K.; Tani, Y.; Ogata, K.; Agric. Biol. Chem. 37, 1335-1340 (1973)
No PubMed abstract available

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
biotin
stimulates
Kocuria rosea
biotin
stimulates
Pseudomonas fluorescens
Inhibitors
Inhibitors
Commentary
Organism
Structure
biotin
-
Bacillus subtilis
biotin
-
Lysinibacillus sphaericus
D-alanine
-
Pseudomonas fluorescens
D-alanine
-
Lysinibacillus sphaericus
D-histidine
-
Lysinibacillus sphaericus
D/L-histidine
-
Alcaligenes faecalis
D/L-histidine
-
Bacillus subtilis
D/L-histidine
-
Citrobacter freundii
D/L-histidine
-
Enterobacter cloacae
D/L-histidine
-
Erwinia aroidea
D/L-histidine
-
Escherichia coli
D/L-histidine
-
Klebsiella aerogenes
D/L-histidine
-
Kocuria rosea
D/L-histidine
-
Pseudomonas fluorescens
D/L-histidine
-
Lysinibacillus sphaericus
glycine
-
Pseudomonas fluorescens
glycine
-
Lysinibacillus sphaericus
L-cysteine
-
Escherichia coli
L-cysteine
-
Lysinibacillus sphaericus
L-cysteine
-
Pseudomonas fluorescens
L-histidine
-
Lysinibacillus sphaericus
L-serine
-
Pseudomonas fluorescens
L-serine
-
Lysinibacillus sphaericus
pyridoxal 5'-phosphate
high concentrations
Lysinibacillus sphaericus
Pyruvic acid
-
Pseudomonas fluorescens
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
6-carboxyhexanoyl-CoA + L-alanine
Alcaligenes faecalis
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Alcaligenes faecalis
?
6-carboxyhexanoyl-CoA + L-alanine
Bacillus subtilis
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Bacillus subtilis
?
6-carboxyhexanoyl-CoA + L-alanine
Escherichia coli
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Escherichia coli
?
6-carboxyhexanoyl-CoA + L-alanine
Enterobacter cloacae
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Enterobacter cloacae
?
6-carboxyhexanoyl-CoA + L-alanine
Lysinibacillus sphaericus
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Lysinibacillus sphaericus
?
6-carboxyhexanoyl-CoA + L-alanine
Kocuria rosea
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Kocuria rosea
?
6-carboxyhexanoyl-CoA + L-alanine
Pseudomonas fluorescens
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Pseudomonas fluorescens
?
6-carboxyhexanoyl-CoA + L-alanine
Klebsiella aerogenes
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Klebsiella aerogenes
?
6-carboxyhexanoyl-CoA + L-alanine
Citrobacter freundii
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Citrobacter freundii
?
6-carboxyhexanoyl-CoA + L-alanine
Erwinia aroidea
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Erwinia aroidea
?
6-carboxyhexanoyl-CoA + L-alanine
Alcaligenes faecalis
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Alcaligenes faecalis
?
6-carboxyhexanoyl-CoA + L-alanine
Bacillus subtilis
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Bacillus subtilis
?
6-carboxyhexanoyl-CoA + L-alanine
Escherichia coli
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Escherichia coli
?
6-carboxyhexanoyl-CoA + L-alanine
Enterobacter cloacae
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Enterobacter cloacae
?
6-carboxyhexanoyl-CoA + L-alanine
Lysinibacillus sphaericus
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Lysinibacillus sphaericus
?
6-carboxyhexanoyl-CoA + L-alanine
Kocuria rosea
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Kocuria rosea
?
6-carboxyhexanoyl-CoA + L-alanine
Pseudomonas fluorescens
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Pseudomonas fluorescens
?
6-carboxyhexanoyl-CoA + L-alanine
Klebsiella aerogenes
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Klebsiella aerogenes
?
6-carboxyhexanoyl-CoA + L-alanine
Citrobacter freundii
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Citrobacter freundii
?
6-carboxyhexanoyl-CoA + L-alanine
Erwinia aroidea
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Erwinia aroidea
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Alcaligenes faecalis
-
-
-
Bacillus subtilis
-
-
-
Citrobacter freundii
-
-
-
Enterobacter cloacae
-
-
-
Erwinia aroidea
-
-
-
Escherichia coli
-
-
-
Klebsiella aerogenes
-
-
-
Kocuria rosea
-
-
-
Lysinibacillus sphaericus
-
-
-
Pseudomonas fluorescens
-
-
-
Purification (Commentary)
Commentary
Organism
partial
Pseudomonas fluorescens
Specific Activity [micromol/min/mg]
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
additional information
-
crude cell-extracts from various organism
Alcaligenes faecalis
additional information
-
crude cell-extracts from various organism
Bacillus subtilis
additional information
-
crude cell-extracts from various organism
Citrobacter freundii
additional information
-
crude cell-extracts from various organism
Enterobacter cloacae
additional information
-
crude cell-extracts from various organism
Erwinia aroidea
additional information
-
crude cell-extracts from various organism
Escherichia coli
additional information
-
crude cell-extracts from various organism
Klebsiella aerogenes
additional information
-
crude cell-extracts from various organism
Kocuria rosea
additional information
-
crude cell-extracts from various organism
Lysinibacillus sphaericus
additional information
-
crude cell-extracts from various organism
Pseudomonas fluorescens
0.00016
-
-
Pseudomonas fluorescens
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Alcaligenes faecalis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Alcaligenes faecalis
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Bacillus subtilis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Bacillus subtilis
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Escherichia coli
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Escherichia coli
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Enterobacter cloacae
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Enterobacter cloacae
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Lysinibacillus sphaericus
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Lysinibacillus sphaericus
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Kocuria rosea
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Kocuria rosea
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Pseudomonas fluorescens
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Pseudomonas fluorescens
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Klebsiella aerogenes
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Klebsiella aerogenes
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Citrobacter freundii
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Citrobacter freundii
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Erwinia aroidea
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Erwinia aroidea
?
6-carboxyhexanoyl-CoA + L-alanine
L-cysteine cannot replace L-alanine
487051
Lysinibacillus sphaericus
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Lysinibacillus sphaericus
?
6-carboxyhexanoyl-CoA + L-alanine
L-cysteine cannot replace L-alanine
487051
Kocuria rosea
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Kocuria rosea
?
6-carboxyhexanoyl-CoA + L-alanine
L-cysteine cannot replace L-alanine
487051
Pseudomonas fluorescens
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Pseudomonas fluorescens
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Alcaligenes faecalis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Alcaligenes faecalis
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Bacillus subtilis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Bacillus subtilis
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Escherichia coli
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Escherichia coli
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Enterobacter cloacae
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Enterobacter cloacae
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Lysinibacillus sphaericus
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Lysinibacillus sphaericus
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Kocuria rosea
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Kocuria rosea
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Pseudomonas fluorescens
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Pseudomonas fluorescens
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Klebsiella aerogenes
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Klebsiella aerogenes
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Citrobacter freundii
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Citrobacter freundii
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Erwinia aroidea
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Erwinia aroidea
?
Cofactor
Cofactor
Commentary
Organism
Structure
pyridoxal 5'-phosphate
-
Alcaligenes faecalis
pyridoxal 5'-phosphate
-
Bacillus subtilis
pyridoxal 5'-phosphate
-
Citrobacter freundii
pyridoxal 5'-phosphate
-
Enterobacter cloacae
pyridoxal 5'-phosphate
-
Erwinia aroidea
pyridoxal 5'-phosphate
-
Klebsiella aerogenes
pyridoxal 5'-phosphate
-
Kocuria rosea
pyridoxal 5'-phosphate
dependent on
Lysinibacillus sphaericus
pyridoxal 5'-phosphate
-
Pseudomonas fluorescens
pyridoxal 5'-phosphate
-
Escherichia coli
Ki Value [mM]
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
0.99
-
L-cysteine
-
Lysinibacillus sphaericus
1.24
-
D-alanine
-
Lysinibacillus sphaericus
1.5
-
L-serine
-
Lysinibacillus sphaericus
3.33
-
glycine
-
Lysinibacillus sphaericus
3.75
-
D-histidine
-
Lysinibacillus sphaericus
5.6
-
L-histidine
-
Lysinibacillus sphaericus
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
biotin
stimulates
Kocuria rosea
biotin
stimulates
Pseudomonas fluorescens
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
pyridoxal 5'-phosphate
-
Alcaligenes faecalis
pyridoxal 5'-phosphate
-
Bacillus subtilis
pyridoxal 5'-phosphate
-
Citrobacter freundii
pyridoxal 5'-phosphate
-
Enterobacter cloacae
pyridoxal 5'-phosphate
-
Erwinia aroidea
pyridoxal 5'-phosphate
-
Klebsiella aerogenes
pyridoxal 5'-phosphate
-
Kocuria rosea
pyridoxal 5'-phosphate
dependent on
Lysinibacillus sphaericus
pyridoxal 5'-phosphate
-
Pseudomonas fluorescens
pyridoxal 5'-phosphate
-
Escherichia coli
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
biotin
-
Bacillus subtilis
biotin
-
Lysinibacillus sphaericus
D-alanine
-
Pseudomonas fluorescens
D-alanine
-
Lysinibacillus sphaericus
D-histidine
-
Lysinibacillus sphaericus
D/L-histidine
-
Alcaligenes faecalis
D/L-histidine
-
Bacillus subtilis
D/L-histidine
-
Citrobacter freundii
D/L-histidine
-
Enterobacter cloacae
D/L-histidine
-
Erwinia aroidea
D/L-histidine
-
Escherichia coli
D/L-histidine
-
Klebsiella aerogenes
D/L-histidine
-
Kocuria rosea
D/L-histidine
-
Pseudomonas fluorescens
D/L-histidine
-
Lysinibacillus sphaericus
glycine
-
Pseudomonas fluorescens
glycine
-
Lysinibacillus sphaericus
L-cysteine
-
Escherichia coli
L-cysteine
-
Lysinibacillus sphaericus
L-cysteine
-
Pseudomonas fluorescens
L-histidine
-
Lysinibacillus sphaericus
L-serine
-
Pseudomonas fluorescens
L-serine
-
Lysinibacillus sphaericus
pyridoxal 5'-phosphate
high concentrations
Lysinibacillus sphaericus
Pyruvic acid
-
Pseudomonas fluorescens
Ki Value [mM] (protein specific)
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
0.99
-
L-cysteine
-
Lysinibacillus sphaericus
1.24
-
D-alanine
-
Lysinibacillus sphaericus
1.5
-
L-serine
-
Lysinibacillus sphaericus
3.33
-
glycine
-
Lysinibacillus sphaericus
3.75
-
D-histidine
-
Lysinibacillus sphaericus
5.6
-
L-histidine
-
Lysinibacillus sphaericus
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
6-carboxyhexanoyl-CoA + L-alanine
Alcaligenes faecalis
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Alcaligenes faecalis
?
6-carboxyhexanoyl-CoA + L-alanine
Bacillus subtilis
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Bacillus subtilis
?
6-carboxyhexanoyl-CoA + L-alanine
Escherichia coli
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Escherichia coli
?
6-carboxyhexanoyl-CoA + L-alanine
Enterobacter cloacae
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Enterobacter cloacae
?
6-carboxyhexanoyl-CoA + L-alanine
Lysinibacillus sphaericus
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Lysinibacillus sphaericus
?
6-carboxyhexanoyl-CoA + L-alanine
Kocuria rosea
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Kocuria rosea
?
6-carboxyhexanoyl-CoA + L-alanine
Pseudomonas fluorescens
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Pseudomonas fluorescens
?
6-carboxyhexanoyl-CoA + L-alanine
Klebsiella aerogenes
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Klebsiella aerogenes
?
6-carboxyhexanoyl-CoA + L-alanine
Citrobacter freundii
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Citrobacter freundii
?
6-carboxyhexanoyl-CoA + L-alanine
Erwinia aroidea
i.e. pimeloyl-CoA
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Erwinia aroidea
?
6-carboxyhexanoyl-CoA + L-alanine
Alcaligenes faecalis
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Alcaligenes faecalis
?
6-carboxyhexanoyl-CoA + L-alanine
Bacillus subtilis
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Bacillus subtilis
?
6-carboxyhexanoyl-CoA + L-alanine
Escherichia coli
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Escherichia coli
?
6-carboxyhexanoyl-CoA + L-alanine
Enterobacter cloacae
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Enterobacter cloacae
?
6-carboxyhexanoyl-CoA + L-alanine
Lysinibacillus sphaericus
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Lysinibacillus sphaericus
?
6-carboxyhexanoyl-CoA + L-alanine
Kocuria rosea
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Kocuria rosea
?
6-carboxyhexanoyl-CoA + L-alanine
Pseudomonas fluorescens
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Pseudomonas fluorescens
?
6-carboxyhexanoyl-CoA + L-alanine
Klebsiella aerogenes
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Klebsiella aerogenes
?
6-carboxyhexanoyl-CoA + L-alanine
Citrobacter freundii
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Citrobacter freundii
?
6-carboxyhexanoyl-CoA + L-alanine
Erwinia aroidea
reaction in biotin biosynthesis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
Erwinia aroidea
?
Purification (Commentary) (protein specific)
Commentary
Organism
partial
Pseudomonas fluorescens
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
additional information
-
crude cell-extracts from various organism
Alcaligenes faecalis
additional information
-
crude cell-extracts from various organism
Bacillus subtilis
additional information
-
crude cell-extracts from various organism
Citrobacter freundii
additional information
-
crude cell-extracts from various organism
Enterobacter cloacae
additional information
-
crude cell-extracts from various organism
Erwinia aroidea
additional information
-
crude cell-extracts from various organism
Escherichia coli
additional information
-
crude cell-extracts from various organism
Klebsiella aerogenes
additional information
-
crude cell-extracts from various organism
Kocuria rosea
additional information
-
crude cell-extracts from various organism
Lysinibacillus sphaericus
additional information
-
crude cell-extracts from various organism
Pseudomonas fluorescens
0.00016
-
-
Pseudomonas fluorescens
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Alcaligenes faecalis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Alcaligenes faecalis
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Bacillus subtilis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Bacillus subtilis
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Escherichia coli
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Escherichia coli
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Enterobacter cloacae
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Enterobacter cloacae
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Lysinibacillus sphaericus
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Lysinibacillus sphaericus
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Kocuria rosea
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Kocuria rosea
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Pseudomonas fluorescens
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Pseudomonas fluorescens
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Klebsiella aerogenes
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Klebsiella aerogenes
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Citrobacter freundii
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Citrobacter freundii
?
6-carboxyhexanoyl-CoA + L-alanine
i.e. pimeloyl-CoA
487051
Erwinia aroidea
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Erwinia aroidea
?
6-carboxyhexanoyl-CoA + L-alanine
L-cysteine cannot replace L-alanine
487051
Lysinibacillus sphaericus
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Lysinibacillus sphaericus
?
6-carboxyhexanoyl-CoA + L-alanine
L-cysteine cannot replace L-alanine
487051
Kocuria rosea
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Kocuria rosea
?
6-carboxyhexanoyl-CoA + L-alanine
L-cysteine cannot replace L-alanine
487051
Pseudomonas fluorescens
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Pseudomonas fluorescens
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Alcaligenes faecalis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Alcaligenes faecalis
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Bacillus subtilis
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Bacillus subtilis
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Escherichia coli
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Escherichia coli
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Enterobacter cloacae
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Enterobacter cloacae
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Lysinibacillus sphaericus
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Lysinibacillus sphaericus
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Kocuria rosea
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Kocuria rosea
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Pseudomonas fluorescens
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Pseudomonas fluorescens
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Klebsiella aerogenes
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Klebsiella aerogenes
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Citrobacter freundii
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Citrobacter freundii
?
6-carboxyhexanoyl-CoA + L-alanine
reaction in biotin biosynthesis
487051
Erwinia aroidea
8-amino-7-oxononanoate + CoA + CO2
i.e. 7-oxo-8-amino-pelargonic acid
487051
Erwinia aroidea
?
Other publictions for EC 2.3.1.47
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [░C]
Temperature Range [░C]
Temperature Stability [░C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [░C] (protein specific)
Temperature Range [░C] (protein specific)
Temperature Stability [░C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
736245
Fan
Structure and function of Myco ...
Mycolicibacterium smegmatis, Mycolicibacterium smegmatis ATCC 700084
Int. J. Biochem. Cell Biol.
58
71-80
2015
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6
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2
2
-
-
-
736946
Hahn
Triazolyl phenyl disulfides: 8 ...
Arabidopsis thaliana
Pestic. Biochem. Physiol.
125
78-83
2015
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1
1
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8
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1
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3
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8
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1
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-
735394
Fan
Purification and X-ray crystal ...
Mycolicibacterium smegmatis, Mycolicibacterium smegmatis ATCC 700084
Acta Crystallogr. Sect. F
70
1372-1375
2014
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1
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4
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2
1
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1
1
-
-
-
719127
Kubota
Detection and characterization ...
Aquifex aeolicus, Escherichia coli, Geobacillus kaustophilus, Geobacillus kaustophilus JCM 12893, Hungateiclostridium thermocellum, Hungateiclostridium thermocellum ATCC 27405, Symbiobacterium thermophilum, Symbiobacterium thermophilum IAM14863, Thermosynechococcus elongatus
Biosci. Biotechnol. Biochem.
76
685-690
2012
-
-
6
-
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-
-
8
-
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6
-
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24
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6
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6
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15
6
6
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6
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6
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6
6
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8
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6
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6
-
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6
-
15
6
6
-
6
-
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-
-
-
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-
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-
7
7
719203
Cho
-
The identification of binding ...
Arabidopsis thaliana
Bull. Korean Chem. Soc.
33
1597-1602
2012
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17
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17
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17
17
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1
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-
-
-
718696
Turbeville
Functional asymmetry for the a ...
Escherichia coli
Arch. Biochem. Biophys.
511
107-117
2011
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1
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1
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4
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1
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2
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4
4
720623
Hwang
-
Validation of 7-keto-8-aminope ...
Arabidopsis thaliana
Pestic. Biochem. Physiol.
97
24-31
2010
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1
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1
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1
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2
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1
1
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-
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-
702483
Mann
Inhibition of 7,8-diaminopelar ...
Escherichia coli, Escherichia coli C268, Mycobacterium tuberculosis
Biochimie
91
826-834
2009
-
2
2
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3
2
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3
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4
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11
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2
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11
2
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6
2
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673041
Kerbarh
Mechanism of alpha-oxoamine sy ...
Escherichia coli
Chem. Commun. (Camb. )
2006
60-62
2006
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-
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1
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674626
Bhor
Broad substrate stereospecific ...
Mycobacterium tuberculosis
J. Biol. Chem.
281
25076-25088
2006
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1
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2
4
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3
1
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3
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1
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1
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6
1
1
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3
1
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676274
Alexeev
Suicide inhibition of alpha-ox ...
Escherichia coli
Org. Biomol. Chem.
4
1209-1212
2006
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1
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1
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1
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2
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676580
Pinon
Biotin synthesis in plants. Th ...
Arabidopsis thaliana
Plant Physiol.
139
1666-1676
2005
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1
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1
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3
1
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2
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5
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1
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1
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1
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1
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1
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1
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1
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2
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1
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3
1
1
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2
1
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-
-
-
-
487058
Webster
Mechanism of 8-amino-7-oxonona ...
Escherichia coli
Biochemistry
39
516-528
2000
-
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1
1
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1
2
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1
2
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2
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1
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1
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1
1
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-
487054
Ploux
Slow-binding and competitive i ...
Lysinibacillus sphaericus
Eur. J. Biochem.
259
63-70
1999
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1
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5
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3
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1
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487056
Webster
Characterization of 8-amino-7- ...
Escherichia coli, Lysinibacillus sphaericus
Biochem. Soc. Trans.
26
S268
1998
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1
1
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1
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487057
Alexeev
The crystal structure of 8-ami ...
Escherichia coli
J. Mol. Biol.
284
401-419
1998
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1
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487053
Ploux
Mechanistic studies on the 8-a ...
Lysinibacillus sphaericus
Eur. J. Biochem.
236
301-308
1996
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2
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487055
Spinelli
Crystallization and preliminar ...
Lysinibacillus sphaericus
Acta Crystallogr. Sect. D
52
866-868
1996
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1
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487048
Ploux
The 8-amino-7-oxopelargonate s ...
Lysinibacillus sphaericus
Biochem. J.
283
327-331
1992
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1
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3
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3
2
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6
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1
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1
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2
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1
1
2
1
1
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1
2
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-
487049
Otsuka
The Escherichia coli biotin bi ...
Escherichia coli
J. Biol. Chem.
263
19577-19585
1988
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2
2
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
1
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
2
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
1333
Izumi
-
Characterization of biotin bio ...
Lipomyces starkeyi, Lysinibacillus sphaericus, Lysinibacillus sphaericus IFO 3525, Sporidiobolus salmonicolor, Sporobolomyces coprophilus
Agric. Biol. Chem.
45
1983-1989
1981
-
-
-
-
-
-
-
-
-
1
-
9
-
9
-
-
-
-
-
-
4
-
9
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
9
-
-
-
-
-
-
4
-
9
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
487051
Izumi
-
Distribution of 7-keto-8-amino ...
Alcaligenes faecalis, Bacillus subtilis, Citrobacter freundii, Enterobacter cloacae, Erwinia aroidea, Escherichia coli, Klebsiella aerogenes, Kocuria rosea, Lysinibacillus sphaericus, Pseudomonas fluorescens
Agric. Biol. Chem.
37
1335-1340
1973
2
-
-
-
-
-
25
-
-
-
-
20
-
10
-
-
1
-
-
-
11
-
23
-
-
-
-
-
-
-
-
10
6
-
-
2
-
-
10
-
-
-
-
25
6
-
-
-
-
20
-
-
-
1
-
-
11
-
23
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
487052
Izumi
-
Partial purification and some ...
Lysinibacillus sphaericus
Agric. Biol. Chem.
37
1327-1333
1973
-
-
-
-
-
-
21
-
-
1
-
2
-
1
-
-
1
-
-
-
1
1
3
-
2
1
3
-
1
1
-
1
-
-
-
-
-
-
1
-
-
-
-
21
-
-
-
1
-
2
-
-
-
1
-
-
1
1
3
-
2
1
3
-
1
1
-
-
-
-
-
-
-
-
487047
Eidenberg
Synthesis of 7-oxo-8-aminopela ...
Escherichia coli
J. Bacteriol.
96
1291-1297
1968
-
-
-
-
1
-
2
-
-
-
-
2
-
1
-
-
-
-
-
-
1
-
3
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
1
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
1
-
3
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-