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Information on EC 2.3.1.47 - 8-amino-7-oxononanoate synthase

for references in articles please use BRENDA:EC2.3.1.47
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IUBMB Comments
A pyridoxal-phosphate protein. The enzyme catalyses the decarboxylative condensation of L-alanine and pimeloyl-[acyl-carrier protein], a key step in the pathway for biotin biosynthesis. Pimeloyl-CoA can be used with lower efficiency .
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
dapa at, 7,8-diaminopelargonic acid aminotransferase, 8-amino-7-oxopelargonate synthase, kapa synthase, kapas, biof protein, 7-keto-8-aminopelargonic acid synthase, atbiof, 7-keto-8-aminopelargonic acid synthetase, 7-keto-8-aminopelargonate synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein]
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