BRENDA - Enzyme Database show
show all sequences of 2.3.1.181

Lipoate-protein ligase and octanoyltransferase are essential for protein lipoylation in mitochondria of Arabidopsis

Ewald, R.; Hoffmann, C.; Florian, A.; Neuhaus, E.; Fernie, A.R.; Bauwe, H.; Plant Physiol. 165, 978-990 (2014)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
mitochondrion
-
Arabidopsis thaliana
5739
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Arabidopsis thaliana
Q9SXP7
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
pyruvate dehydrogenase E2 domain is exclusively octanoylated by lipoate-protein ligase LPLA, EC 2.7.7.63
737026
Arabidopsis thaliana
?
-
-
-
-
octanoyl-[acyl-carrier protein] + alpha-ketoglutarate dehydrogenase apo-E2 domain
-
737026
Arabidopsis thaliana
alpha-ketoglutarate dehydrogenase E2-domain N6-(octanoyl)lysine + acyl-carrier protein
-
-
-
?
octanoyl-[acyl-carrier protein] + glycine dehydrogenase H-protein
-
737026
Arabidopsis thaliana
glycine dehydrogenase H-protein N6-(octanoyl)lysine + acyl-carrier protein
glycine dehydrogenase H-protein can be octanoylated both by Lip2 or by lipoate-protein ligase LPLA, EC 2.7.7.63
-
-
?
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
mitochondrion
-
Arabidopsis thaliana
5739
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
pyruvate dehydrogenase E2 domain is exclusively octanoylated by lipoate-protein ligase LPLA, EC 2.7.7.63
737026
Arabidopsis thaliana
?
-
-
-
-
octanoyl-[acyl-carrier protein] + alpha-ketoglutarate dehydrogenase apo-E2 domain
-
737026
Arabidopsis thaliana
alpha-ketoglutarate dehydrogenase E2-domain N6-(octanoyl)lysine + acyl-carrier protein
-
-
-
?
octanoyl-[acyl-carrier protein] + glycine dehydrogenase H-protein
-
737026
Arabidopsis thaliana
glycine dehydrogenase H-protein N6-(octanoyl)lysine + acyl-carrier protein
glycine dehydrogenase H-protein can be octanoylated both by Lip2 or by lipoate-protein ligase LPLA, EC 2.7.7.63
-
-
?
Other publictions for EC 2.3.1.181
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
726128
Ewald
Two redundant octanoyltransfer ...
Arabidopsis thaliana
Plant Biol.
16
35-42
2014
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2
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737026
Ewald
Lipoate-protein ligase and oct ...
Arabidopsis thaliana
Plant Physiol.
165
978-990
2014
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1
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1
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Protein-protein interactions i ...
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Martin
A novel two-gene requirement f ...
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Mol. Microbiol.
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Biochemistry
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10024-10036
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Scavenging of cytosolic octano ...
Escherichia coli
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Knockout studies reveal an imp ...
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Escherichia coli
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2005
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Nesbitt
Expression, purification, and ...
Escherichia coli
Protein Expr. Purif.
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2005
2
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1
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2
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The Escherichia coli lipB gene ...
Escherichia coli
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1582-1589
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