BRENDA - Enzyme Database show
show all sequences of 2.3.1.161

LovG: The thioesterase required for dihydromonacolin L release and lovastatin nonaketide synthase turnover in lovastatin biosynthesis

Xu, W.; Chooi, Y.; Choi, J.; Li, S.; Vederas, J.; Da Silva, N.; Tang, Y.; Angew. Chem. Int. Ed. Engl. 52, 6472-6475 (2013)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Aspergillus terreus
Q9Y8A5
-
-
General Information
General Information
Commentary
Organism
physiological function
release of reaction product from enzyme LovB is mediated by multifunctional esterase LovG. LovG is also involved in the clearance of aberrant intermediates from LovB
Aspergillus terreus
General Information (protein specific)
General Information
Commentary
Organism
physiological function
release of reaction product from enzyme LovB is mediated by multifunctional esterase LovG. LovG is also involved in the clearance of aberrant intermediates from LovB
Aspergillus terreus
Other publictions for EC 2.3.1.161
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
736314
Cacho
Understanding programming of f ...
Aspergillus terreus
J. Am. Chem. Soc.
137
15688-15691
2015
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735434
Xu
LovG: The thioesterase require ...
Aspergillus terreus
Angew. Chem. Int. Ed. Engl.
52
6472-6475
2013
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701673
Lee
Determination of the extent of ...
Aspergillus terreus
Anal. Biochem.
394
75-80
2009
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706764
Ma
Complete reconstitution of a h ...
Aspergillus terreus
Science
326
589-592
2009
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673594
Ma
Biochemical characterization o ...
Aspergillus terreus
FEBS J.
274
2854-2864
2007
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676287
Burr
Syntheses of conjugated pyrone ...
Aspergillus terreus
Org. Lett.
9
161-164
2007
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660049
Sorensen
Transformations of cyclic nona ...
Aspergillus terreus
Org. Biomol. Chem.
1
50-59
2003
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441503
Auclair
-
Lovastatin nonaketide synthase ...
Aspergillus terreus
J. Am. Chem. Soc.
122
11519-11520
2000
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441505
Hutchinson
Aspects of the biosynthesis of ...
Aspergillus terreus
Antonie van Leeuwenhoek
78
287-295
2000
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441504
Hendrickson
Lovastatin biosynthesis in Asp ...
Aspergillus terreus
Chem. Biol.
6
429-439
1999
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441506
Kennedy
Modulation of polyketide synth ...
Aspergillus terreus
Science
284
1368-1372
1999
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