Cloned (Comment) | Organism |
---|---|
genes and isozymes LOXL1 and LOX, detailed expression analysis in aorta during growth and development, overview | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
LOU and Brown-Norway rats, male inbred BN/Rij rats, two inbred strains with different susceptibilities to arterial fragility, genes and isozymes LOXL1 and LOX | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
aorta | different spatial and temporal expression of LOX and LOXL1 during growth and aging, expression analysis of LOXL1 and LOX in the aorta during the development, growth, and aging of LOU rats, overview | Rattus norvegicus | - |
additional information | high aortic LOX expression early in the development, i.e. embryonic day 15, followed by a drastic reduction in adulthood, whereas LOXL1 is mainly detectable in the intima and media and is expressed throughout life in the LOU rat | Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
LOX | - |
Rattus norvegicus |
LOXL1 | - |
Rattus norvegicus |
lysyl oxidase-like | - |
Rattus norvegicus |
lysyl oxidases | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | role for lysyl oxidase-like, LOXL1, in adult elastin synthesis and a role for its isoform, lysyl oxidase, LOX, in the synthesis of both collagens and elastin during development. Specific roles for LOX and LOXL1 in the synthesis and remodeling of elastic and collagen fibers, overview | Rattus norvegicus |