Cloned (Comment) | Organism |
---|---|
gene bciA | Cereibacter sphaeroides |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
8-vinyl protochlorophyllide a + NADPH + H+ | Cereibacter sphaeroides | is reduced only under conditions in which this pigment accumulates as a result of perturbed formation of chlorophyllide | protochlorophyllide a + NADP+ | - |
? | |
8-vinyl protochlorophyllide a + NADPH + H+ | Cereibacter sphaeroides DSM 158 | is reduced only under conditions in which this pigment accumulates as a result of perturbed formation of chlorophyllide | protochlorophyllide a + NADP+ | - |
? | |
C8-vinyl chlorophyllide a + NADPH + H+ | Cereibacter sphaeroides | 8V Chlide is the preferred substrate for BciA, with high substrate specificity | chlorophyllide a + NADP+ | - |
? | |
C8-vinyl chlorophyllide a + NADPH + H+ | Cereibacter sphaeroides DSM 158 | 8V Chlide is the preferred substrate for BciA, with high substrate specificity | chlorophyllide a + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cereibacter sphaeroides | Q3IXP7 | - |
- |
Cereibacter sphaeroides DSM 158 | Q3IXP7 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
8-vinyl protochlorophyllide a + NADPH + H+ | is reduced only under conditions in which this pigment accumulates as a result of perturbed formation of chlorophyllide | Cereibacter sphaeroides | protochlorophyllide a + NADP+ | - |
? | |
8-vinyl protochlorophyllide a + NADPH + H+ | is reduced only under conditions in which this pigment accumulates as a result of perturbed formation of chlorophyllide | Cereibacter sphaeroides DSM 158 | protochlorophyllide a + NADP+ | - |
? | |
C8-vinyl chlorophyllide a + NADPH + H+ | 8V Chlide is the preferred substrate for BciA, with high substrate specificity | Cereibacter sphaeroides | chlorophyllide a + NADP+ | - |
? | |
C8-vinyl chlorophyllide a + NADPH + H+ | preferred substrate with high substrate specificity | Cereibacter sphaeroides | chlorophyllide a + NADP+ | - |
? | |
C8-vinyl chlorophyllide a + NADPH + H+ | 8V Chlide is the preferred substrate for BciA, with high substrate specificity | Cereibacter sphaeroides DSM 158 | chlorophyllide a + NADP+ | - |
? | |
C8-vinyl chlorophyllide a + NADPH + H+ | preferred substrate with high substrate specificity | Cereibacter sphaeroides DSM 158 | chlorophyllide a + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
8V reductase | - |
Cereibacter sphaeroides |
8VR | - |
Cereibacter sphaeroides |
BciA | - |
Cereibacter sphaeroides |
C8-vinyl reductase | - |
Cereibacter sphaeroides |
nucleoside-diphosphate-sugar epimerase | UniProt | Cereibacter sphaeroides |
RSP_3070 | - |
Cereibacter sphaeroides |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Cereibacter sphaeroides |
Organism | Comment | Expression |
---|---|---|
Cereibacter sphaeroides | generation of an enzyme BciA knockout mutant and recombinant expression of Synechocystis sp. PCC6803 gene bciB in the mutant, gene bciB is unable to restore the accumulation of pigments containing groups reduced at the C8 position | additional information |
General Information | Comment | Organism |
---|---|---|
evolution | two unrelated classes of C8-vinyl reductase are known to exist, BciA and BciB | Cereibacter sphaeroides |
metabolism | the majority of (B)Chls utilized for light-harvesting carry an ethyl group at the C8 position (8E) of the macrocycle. This group is produced by the reduction of a vinyl group (8V), catalysed by an 8V reductase, 8VR, resulting in the production of an 8E pigment. Although BciA demonstrates flexible specificity, biosynthetic heterogeneity does not occur in this organism when its preferred substrate is present, implying that, in this case, the biosynthetic pathway is linear | Cereibacter sphaeroides |