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Literature summary for 1.17.1.3 extracted from

  • Pfeiffer, J.; Kuehnel, C.; Brandt, J.; Duy, D.; Punyasiri, P.A.; Forkmann, G.; Fischer, T.C.
    Biosynthesis of flavan 3-ols by leucoanthocyanidin 4-reductases and anthocyanidin reductases in leaves of grape (Vitis vinifera L.), apple (Malus x domestica Borkh.) and other crops (2006), Plant Physiol. Biochem., 44, 323-334.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Malus domestica Q5D7Y1 isoform LAR2
-
Malus domestica Q5D7Y2 isoform LAR1
-
Vitis vinifera Q3S9L6 isoform LAR2
-
Vitis vinifera Q4W2K5 isoform LAR1
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf both isoforms LAR1 and LAR2 decreasing expression from early to late stages of leaf development Vitis vinifera
-
leaf both isoforms LAR1 and LAR2 decreasing expression from early to late stages of leaf development Malus domestica
-
leaf both isoforms LAR1 and LAR2 show decreasing expression from early to late stages of leaf development Malus domestica
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,3-trans-3,4-cis-leucocyanidin + NADPH + H+ both isoforms LAR1 and LAR2 Vitis vinifera (2R,3S)-catechin + NADP+ + H2O
-
?
2,3-trans-3,4-cis-leucocyanidin + NADPH + H+ both isoforms LAR1 and LAR2 Malus domestica (2R,3S)-catechin + NADP+ + H2O
-
?
3,4-cis-leucopelargonidin + NADPH both isoforms LAR1 and LAR2 Vitis vinifera ? + NADP+ + H2O
-
?
3,4-cis-leucopelargonidin + NADPH substrate only for isoform LAR2 Malus domestica ? + NADP+ + H2O
-
?
leucodelphinidin + NADPH both isoforms LAR1 and LAR2 Vitis vinifera ? + NADP+ + H2O
-
?
leucodelphinidin + NADPH both isoforms LAR1 and LAR2 Malus domestica ? + NADP+ + H2O
-
?
luteoforol + NADPH i.e. 3-deoxyleucocyanidin, both isoforms LAR1 and LAR2 Vitis vinifera luteoliflavan + NADP+ + H2O
-
?
luteoforol + NADPH i.e. 3-deoxyleucocyanidin, both isoforms LAR1 and LAR2 Malus domestica luteoliflavan + NADP+ + H2O
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
-
Malus domestica
37
-
-
Malus domestica
37
-
both isoforms LAR1 and LAR2 Vitis vinifera

pH Range

pH Minimum pH Maximum Comment Organism
6 7 both isoforms LAR1 and LAR2 Vitis vinifera
6 7 both isoforms LAR1 and LAR2 Malus domestica