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Literature summary for 1.1.5.14 extracted from

  • Hibino, Y.; Kawai, S.; Kitazumi, Y.; Shirai, O.; Kano, K.
    Protein-engineering improvement of direct electron transfer-type bioelectrocatalytic properties of D-fructose dehydrogenase (2019), Electrochemistry, 87, 47-51 .
No PubMed abstract available
Search for more literature for 1.1.5.14

Protein Variants

Protein Variants Comment Organism
additional information in mutant M450QDELTA1cFDH, 143 amino acid residues involving heme 1c are removed and M450 as the sixth axial ligand of heme 2c is replaced with glutamine to negatively shift the formal potential of heme 2c Gluconobacter japonicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-fructose + an ubiquinone Gluconobacter japonicus
-
 5-dehydro-D-fructose + an ubiquinol
-
 ?
D-fructose + an ubiquinone Gluconobacter japonicus NBRC 3260
-
 5-dehydro-D-fructose + an ubiquinol
-
 ?

Organism

Organism UniProt Comment Textmining
Gluconobacter japonicus
-
-
-
Gluconobacter japonicus NBRC 3260
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-fructose + an ubiquinone
-
 Gluconobacter japonicus 5-dehydro-D-fructose + an ubiquinol
-
 ?
D-fructose + an ubiquinone
-
 Gluconobacter japonicus NBRC 3260 5-dehydro-D-fructose + an ubiquinol
-
 ?

Subunits

Subunits Comment Organism
heterotrimer 1 * 67000 + 1 * 51000 + 1 * 20000, calculated from amino acid sequence Gluconobacter japonicus

Synonyms

Synonyms Comment Organism
D-fructose dehydrogenase
-
 Gluconobacter japonicus
FDH
-
 Gluconobacter japonicus

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Gluconobacter japonicus
heme c the enzyme contains three heme c moieties Gluconobacter japonicus