Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dihydrolipoate | competitive inhibition of 2-hydroxybutyrate oxidation | Rattus sp. |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.03 | - |
propane-1,3-dithiol-glyoxylate adduct | - |
Rattus sp. | |
0.3 | - |
O2 | oxidation of 2-hydroxybutyrate | Rattus sp. | |
0.4 | - |
N-acetylcysteamine-glyoxylate adduct | - |
Rattus sp. | |
0.46 | - |
O2 | oxidation of propane-1,3-dithiol-glyoxylate adduct | Rattus sp. | |
0.7 | - |
pantetheine-glyoxylate adduct | - |
Rattus sp. | |
0.75 | - |
2-mercaptoethanol-glyoxylate adduct | - |
Rattus sp. | |
1.2 | - |
DL-2-hydroxybutyrate | - |
Rattus sp. | |
2.2 | - |
coenzyme A-glyoxylate adduct | - |
Rattus sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
DL-2-hydroxybutyrate + O2 | Rattus sp. | - |
2-oxobutyrate + H2O2 | - |
? | |
glyoxylate + O2 | Rattus sp. | in the absence of any nucleophile less than 2% of the activity compared to glycolate | ? + H2O2 | - |
? | |
thiol-glyoxylate adducts + O2 | Rattus sp. | may be the physiological substrates | an oxalyl thioester + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus sp. | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Rattus sp. | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-mercaptoethanol-glyoxylate adduct + O2 | - |
Rattus sp. | ? | - |
r | |
coenzyme A-glyoxylate adduct + O2 | - |
Rattus sp. | ? | - |
r | |
DL-2-hydroxybutyrate + O2 | - |
Rattus sp. | 2-oxobutyrate + H2O2 | - |
? | |
glyoxylate + O2 | in the absence of any nucleophile less than 2% of the activity compared to glycolate | Rattus sp. | ? + H2O2 | - |
? | |
N-acetylcysteamine-glyoxylate adduct + O2 | - |
Rattus sp. | ? | - |
r | |
pantetheine-glyoxylate adduct + O2 | - |
Rattus sp. | ? | - |
r | |
propane-1,3-dithiol-glyoxylate adduct + O2 | - |
Rattus sp. | ? | - |
r | |
thiol-glyoxylate adducts + O2 | may be the physiological substrates | Rattus sp. | an oxalyl thioester + H2O2 | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.13 | - |
dihydrolipoate | - |
Rattus sp. |