Inhibitors | Comment | Organism | Structure |
---|---|---|---|
11-oxoandrosterone | 0.0021 mM, 50% inhibition of oxido-reductase reaction | Rattus norvegicus | |
11-oxoprogesterone | 0.0095 mM, 50% inhibition of oxido-reductase reaction | Rattus norvegicus | |
11-oxotestosterone | 0.018 mM, 50% inhibition of oxido-reductase reaction | Rattus norvegicus | |
11beta-hydroxyandrosterone | 0.07 mM, 50% inhibition of dehydrogenase reaction | Rattus norvegicus | |
11beta-hydroxydehydroepiandrosterone | 0.003 mM, 50% inhibition of dehydrogenase reaction | Rattus norvegicus | |
11beta-hydroxyprogesterone | 0.0004 mM, 50% inhibition of dehydrogenase reaction | Rattus norvegicus | |
11beta-hydroxytestosterone | 0.0017 mM, 50% inhibition of dehydrogenase reaction | Rattus norvegicus | |
testosterone | 0.003 mM, 50% inhibition of oxido-reductase reaction; 0.02 mM, 50% inhibition of dehydrogenase reaction | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0073 | - |
11-Dehydrocorticosterone | 37°C, pH 7.4 | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
51500 | - |
x * 51500, immunoblot | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
11-dehydrocorticosterone + NADPH | Rattus norvegicus | - |
corticosterone + NADP+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Rattus norvegicus | - |
Leydig cell | - |
Rattus norvegicus | - |
testis | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
11-dehydrocorticosterone + NADPH | - |
Rattus norvegicus | corticosterone + NADP+ | - |
r |
Subunits | Comment | Organism |
---|---|---|
? | x * 51500, immunoblot | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
11beta-HSD1 | - |
Rattus norvegicus |
11beta-hydroxysteroid dehydrogenase | - |
Rattus norvegicus |