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Disease on EC 6.1.1.11 - serine-tRNA ligase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Alkalosis
Mutations in the mitochondrial seryl-tRNA synthetase cause hyperuricemia, pulmonary hypertension, renal failure in infancy and alkalosis, HUPRA syndrome.
Ataxia Telangiectasia
Phosphorylation of seryl-tRNA synthetase by ATM/ATR is essential for hypoxia-induced angiogenesis.
Targeting Angiogenesis by Blocking the ATM-SerRS-VEGFA Pathway for UV-Induced Skin Photodamage and Melanoma Growth.
Breast Neoplasms
Glucose-sensitive acetylation of Seryl tRNA synthetase regulates lipid synthesis in breast cancer.
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging.
Through tissue imaging of a live breast cancer tumour model using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS).
Carcinoma
Image-guided surgery of head and neck carcinoma in rabbit models by intra-operatively defining tumour-infiltrated margins and metastatic lymph nodes.
Cystic Fibrosis
Simple multiplex genotyping by surface-enhanced resonance Raman scattering.
Surface enhanced resonance Raman scattering (SERRS)--a first example of its use in multiplex genotyping.
Deafness
Characterization and tRNA recognition of mammalian mitochondrial seryl-tRNA synthetase.
Novel coding-region polymorphisms in mitochondrial seryl-tRNA synthetase (SARSM) and mitoribosomal protein S12 (RPMS12) genes in DFNA4 autosomal dominant deafness families.
Glioblastoma
An EGFRvIII targeted dual-modal gold nanoprobe for imaging-guided brain tumor surgery.
High Precision Imaging of Microscopic Spread of Glioblastoma with a Targeted Ultrasensitive SERRS Molecular Imaging Probe.
Hypertension, Pulmonary
Mutations in the mitochondrial seryl-tRNA synthetase cause hyperuricemia, pulmonary hypertension, renal failure in infancy and alkalosis, HUPRA syndrome.
Splicing Defect in Mitochondrial Seryl-tRNA Synthetase Gene Causes Progressive Spastic Paresis Instead of HUPRA Syndrome.
Infections
SERRS immunoassay for quantitative human CRP analysis.
Liver Diseases
PreS1 peptide-functionalized gold nanostructures with SERRS tags for efficient liver cancer cell targeting.
Liver Neoplasms
PreS1 peptide-functionalized gold nanostructures with SERRS tags for efficient liver cancer cell targeting.
Lymphatic Metastasis
Detection of Lymph Node Metastases with SERRS Nanoparticles.
Malaria
Magnetic field enriched surface enhanced resonance Raman spectroscopy for early malaria diagnosis.
Optimization of Fe3O4@Ag nanoshells in magnetic field-enriched surface-enhanced resonance Raman scattering for malaria diagnosis.
Surface-enhanced resonance Raman scattering of hemoproteins and those in complicated biological systems.
Melanoma
Targeting Angiogenesis by Blocking the ATM-SerRS-VEGFA Pathway for UV-Induced Skin Photodamage and Melanoma Growth.
Muscle Spasticity
Splicing Defect in Mitochondrial Seryl-tRNA Synthetase Gene Causes Progressive Spastic Paresis Instead of HUPRA Syndrome.
Neoplasm Metastasis
Detection of Lymph Node Metastases with SERRS Nanoparticles.
Tissue factor-specific ultra-bright SERRS nanostars for Raman detection of pulmonary micrometastases.
Neoplasm Micrometastasis
Tissue factor-specific ultra-bright SERRS nanostars for Raman detection of pulmonary micrometastases.
Neoplasms
Au@pNIPAM SERRS Tags for Multiplex Immunophenotyping Cellular Receptors and Imaging Tumor Cells.
Bioimaging: Au@pNIPAM SERRS Tags for Multiplex Immunophenotyping Cellular Receptors and Imaging Tumor Cells (Small 33/2015).
Chelator-Free Radiolabeling of SERRS Nanoparticles for Whole-Body PET and Intraoperative Raman Imaging.
Detection of Lymph Node Metastases with SERRS Nanoparticles.
Graphene oxide-encoded Ag nanoshells with single-particle detection sensitivity towards cancer cell imaging based on SERRS.
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
High Precision Imaging of Microscopic Spread of Glioblastoma with a Targeted Ultrasensitive SERRS Molecular Imaging Probe.
High-speed Raman-encoded molecular imaging of freshly excised tissue surfaces with topically applied SERRS nanoparticles.
Image-guided surgery of head and neck carcinoma in rabbit models by intra-operatively defining tumour-infiltrated margins and metastatic lymph nodes.
Non-invasive In Vivo Imaging of Cancer Using Surface-Enhanced Spatially Offset Raman Spectroscopy (SESORS).
PreS1 peptide-functionalized gold nanostructures with SERRS tags for efficient liver cancer cell targeting.
Prussian Blue as a Highly Sensitive and Background-Free Resonant Raman Reporter.
Quantitative ratiometric discrimination between noncancerous and cancerous prostate cells based on neuropilin-1 overexpression.
Raman spectroscopy in biomedicine: new advances in SERRS cancer imaging.
Rational design of a chalcogenopyrylium-based surface-enhanced resonance Raman scattering nanoprobe with attomolar sensitivity.
Safe core-satellite magneto-plasmonic nanostructures for efficient targeting and photothermal treatment of tumor cells.
Sensitive Trimodal Magnetic Resonance Imaging-Surface-Enhanced Resonance Raman Scattering-Fluorescence Detection of Cancer Cells with Stable Magneto-Plasmonic Nanoprobes.
SERRS multiplexing with multivalent nanostructures for the identification and enumeration of epithelial and mesenchymal cells.
Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence.
Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging.
Surface-Enhanced Resonance Raman Scattering-Guided Brain Tumor Surgery Showing Prognostic Benefit in Rat Models.
Pancreatic Neoplasms
Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging.
Paresis
Splicing Defect in Mitochondrial Seryl-tRNA Synthetase Gene Causes Progressive Spastic Paresis Instead of HUPRA Syndrome.
Prostatic Neoplasms
Detection of Lymph Node Metastases with SERRS Nanoparticles.
Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging.
Renal Insufficiency
Mutations in the mitochondrial seryl-tRNA synthetase cause hyperuricemia, pulmonary hypertension, renal failure in infancy and alkalosis, HUPRA syndrome.
Splicing Defect in Mitochondrial Seryl-tRNA Synthetase Gene Causes Progressive Spastic Paresis Instead of HUPRA Syndrome.
Sarcoma
Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging.
Stroke
In situ surface enhanced resonance Raman scattering (SERRS) spectroscopy of biro inks--long-term stability of colloid treated samples.