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Information on EC 4.2.1.100 - cyclohexa-1,5-dienecarbonyl-CoA hydratase
for references in articles please use BRENDA:EC4.2.1.100
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EC Tree 4 Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.100 cyclohexa-1,5-dienecarbonyl-CoA hydratase
IUBMB Comments
Forms part of the anaerobic benzoate degradation pathway, which also includes EC 1.3.8.6 [glutaryl-CoA dehydrogenase (ETF)], EC 1.3.7.8 (benzoyl-CoA reductase) and EC 4.2.1.55 (3-hydroyxbutyryl-CoA dehydratase).
The expected taxonomic range for this enzyme is: Bacteria, Archaea
- 4.2.1.100
- benzoyl-coa
- aromatica
-
thauera
-
denitrifying
-
rhodopseudomonas
- palustris
- nad+
-
atp-driven
- crotonyl-coa
- benzene
- co2
-
benzoyl-coenzyme
-
two-electron
-
anoxic
- ferredoxin
- benzoate
Reaction Schemes
showSynonyms
dienoyl-coa hydratase, 1,5-dienoyl-coa hydratase, more
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SYNONYM 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
1,5-dienoyl-CoA hydratase
cyclohexa-1,5-diene-1-carbonyl-CoA hydratase
-
-
-
-
Cyclohexa-1,5-diene-1-carboxyl-CoA hydratase
-
-
-
-
DCH
dienoyl-CoA hydratase
EC 4.2.1.102
-
-
formerly
-
Ferp_1031
dienoyl-CoA hydratase
-
-
-
-
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REACTION
REACTION DIAGRAM
COMMENTARY
ORGANISM
UNIPROT
LITERATURE
6-hydroxycyclohex-1-ene-1-carbonyl-CoA = cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
-
-
-
-
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
addition
-
-
-
-
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PATHWAY SOURCE
PATHWAYS
BRENDA
MetaCyc
benzoyl-CoA degradation II (anaerobic), crotonate fermentation (to acetate and cyclohexane carboxylate)
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SYSTEMATIC NAME
IUBMB Comments
6-hydroxycyclohex-1-enecarbonyl-CoA hydro-lyase (cyclohexa-1,5-dienecarbonyl-CoA-forming)
Forms part of the anaerobic benzoate degradation pathway, which also includes EC 1.3.8.6 [glutaryl-CoA dehydrogenase (ETF)], EC 1.3.7.8 (benzoyl-CoA reductase) and EC 4.2.1.55 (3-hydroyxbutyryl-CoA dehydratase).
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CAS REGISTRY NUMBER
COMMENTARY
214355-79-0
-
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SUBSTRATE
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + H2O
2-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
6-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
cyclohex-1-ene-1-carbonyl-CoA + H2O
2-hydroxycyclohexane-1-carbonyl-CoA
-
Substrates: -
Products: -
Products: -
?
cyclohexa-1,5-dienecarbonyl-CoA + H2O
6-hydroxycyclohex-1-ene-1-carbonyl-CoA
Substrates: trans-1,4 water addition, stereochemistry of 6-hydroxycyclohex-1-ene-1-carboxyl-CoA by NMR analysis
Products: -
Products: -
?
cyclohexa-2,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-2-ene-1-carbonyl-CoA
-
Substrates: only when dithionite is used as an artificial electron donor
Products: -
Products: -
?
additional information
?
-
Substrates: the 1,5-dienoyl-CoA hydratase hydrated the fluorocyclohexa-1,5-dienoyl-CoA isomers to a mixture of the stable 2-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA and the unstable alpha-fluorohydrin 6-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA. The latter spontaneously decomposed to HF and 6-oxo-cyclohexa-1-ene-1-carbonyl-CoA
Products: -
Products: -
?
2-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + H2O
2-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
r
2-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + H2O
2-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
r
6-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
r
6-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
r
6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
Substrates: -
Products: -
Products: -
r
6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
Substrates: -
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-ene-1-carbonyl-CoA
-
Substrates: -
Products: -
Products: -
?
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-ene-1-carbonyl-CoA
Substrates: the enzyme is involved in benzoyl-coenzyme A degradation
Products: -
Products: -
?
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
?
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-ene-1-carbonyl-CoA
Substrates: the enzyme is involved in benzoyl-coenzyme A degradation
Products: -
Products: -
?
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
?
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-ene-1-carbonyl-CoA
-
Substrates: -
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-enecarbonyl-CoA
-
Substrates: -
Products: -
Products: -
?
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-enecarbonyl-CoA
-
Substrates: involved in the benzoyl-CoA pathway
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-enecarbonyl-CoA
-
Substrates: -
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-enecarbonyl-CoA
-
Substrates: involved in the benzoyl-CoA pathway
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-enecarbonyl-CoA
-
Substrates: -
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-enecarbonyl-CoA
-
Substrates: involved in the benzoyl-CoA pathway
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-enecarbonyl-CoA
-
Substrates: -
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-enecarbonyl-CoA
-
Substrates: -
Products: -
Products: -
?
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
r
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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + H2O
2-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
6-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
2-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + H2O
2-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
r
2-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + H2O
2-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
r
6-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
r
6-fluorocyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
r
6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
Substrates: -
Products: -
Products: -
r
6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
Substrates: -
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-ene-1-carbonyl-CoA
Substrates: the enzyme is involved in benzoyl-coenzyme A degradation
Products: -
Products: -
?
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-ene-1-carbonyl-CoA
Substrates: the enzyme is involved in benzoyl-coenzyme A degradation
Products: -
Products: -
?
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-enecarbonyl-CoA
-
Substrates: -
Products: -
Products: -
?
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-enecarbonyl-CoA
-
Substrates: involved in the benzoyl-CoA pathway
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-enecarbonyl-CoA
-
Substrates: involved in the benzoyl-CoA pathway
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-enecarbonyl-CoA
-
Substrates: involved in the benzoyl-CoA pathway
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohex-1-enecarbonyl-CoA
-
Substrates: -
Products: -
Products: -
?
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
r
cyclohexa-1,5-diene-1-carbonyl-CoA + H2O
6-hydroxycyclohexa-1-ene-1-carbonyl-CoA
Substrates: -
Products: -
Products: -
r
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
IMAGE
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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
107
purified recombinant enzyme with substrate cyclohexa-1,5-diene-1-carbonyl-CoA, pH and temperature not specified in the publication
110
110
-
reversible reaction with 6-hydroxycyclohex-1-ene-1-carboxyl-CoA as substrat
110
purified recombinant enzyme with substrate 6-hydroxycyclohex-1-ene-1-carbonyl-CoA, pH and temperature not specified in the publication
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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
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ORGANISM
COMMENTARY
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
SOURCE
additional information
additional information
2-fluoro-benzoate- and benzoate-grown cells
brenda
additional information
-
2-fluoro-benzoate- and benzoate-grown cells
-
brenda
Highest Expressing Human Cell Lines
Cell Line LinksPlease wait a moment until the data is sorted. This message will disappear when the data is sorted.
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
metabolism
physiological function
metabolism
the enzyme is involved in benzoyl-coenzyme A degradation
metabolism
the enzyme is involved in the biodegradation of the environmentally hazardous fluoroaromatics. The 1,5-dienoyl-CoA hydratase (DCH) hydrates the fluoro-1,5-dienoyl-CoA isomers to a mixture of the stable 2-fluoro-6-hydroxy-1-enoyl-CoA and the unstable alpha-fluorohydrin 6-fluoro-6-hydroxy-1-enoyl-CoA. The latter spontaneously decomposes to HF and 6-oxo-cyclohex-1-enoyl-CoA, a common intermediate of the benzoyl-coenzyme A (BzCoA) degradation pathway. 6-Oxo-cyclohex-1-enoyl-CoA hydrolase/hydratase catalyzes the defluorination of 2-fluoro-6-hydroxycyclohex-1-enoyl-CoA to 2-oxo-6-hydroxycyclohex-1-enoyl-CoA and HF again via water addition to an fluorocyclohex-1-enoyl-CoA functionality. Formation of both 3-fluorocyclohexa-1,5-diene-1-carbonyl-CoA and 5-fluorocyclohexa-1,5-diene-1-carbonyl-CoA suggesting a low regioselectivity of benzoyl-coenzyme A (BzCoA) reductase (BCR) for fluorinated BzCoA analogues. Enzyme DCH and bifunctional 6-oxo-cyclohex-1-enoyl-CoA hydrolase (OAH) both initiate defluorination of the 2-fluorocyclohexa-1,5-diene-1-carbonyl-CoA intermediate by 1,4-hydration. Enzyme OAH is competent to hydrate both fluorinated cyclohexa-1,5-diene-carbonyl-CoA isomers and exhibits a similar reactivity as enzyme DCH, and OAH alone is capable of defluorinating both fluorinated cyclohexa-1,5-diene-carbonyl-CoA isomers formed by BCR. Detailed pathway overview
metabolism
-
the enzyme is involved in the biodegradation of the environmentally hazardous fluoroaromatics. The 1,5-dienoyl-CoA hydratase (DCH) hydrates the fluoro-1,5-dienoyl-CoA isomers to a mixture of the stable 2-fluoro-6-hydroxy-1-enoyl-CoA and the unstable alpha-fluorohydrin 6-fluoro-6-hydroxy-1-enoyl-CoA. The latter spontaneously decomposes to HF and 6-oxo-cyclohex-1-enoyl-CoA, a common intermediate of the benzoyl-coenzyme A (BzCoA) degradation pathway. 6-Oxo-cyclohex-1-enoyl-CoA hydrolase/hydratase catalyzes the defluorination of 2-fluoro-6-hydroxycyclohex-1-enoyl-CoA to 2-oxo-6-hydroxycyclohex-1-enoyl-CoA and HF again via water addition to an fluorocyclohex-1-enoyl-CoA functionality. Formation of both 3-fluorocyclohexa-1,5-diene-1-carbonyl-CoA and 5-fluorocyclohexa-1,5-diene-1-carbonyl-CoA suggesting a low regioselectivity of benzoyl-coenzyme A (BzCoA) reductase (BCR) for fluorinated BzCoA analogues. Enzyme DCH and bifunctional 6-oxo-cyclohex-1-enoyl-CoA hydrolase (OAH) both initiate defluorination of the 2-fluorocyclohexa-1,5-diene-1-carbonyl-CoA intermediate by 1,4-hydration. Enzyme OAH is competent to hydrate both fluorinated cyclohexa-1,5-diene-carbonyl-CoA isomers and exhibits a similar reactivity as enzyme DCH, and OAH alone is capable of defluorinating both fluorinated cyclohexa-1,5-diene-carbonyl-CoA isomers formed by BCR. Detailed pathway overview
-
metabolism
-
the enzyme is involved in benzoyl-coenzyme A degradation
-
physiological function
the enzyme is involved in the biodegradation of the environmentally hazardous fluoroaromatics. The 1,5-dienoyl-CoA hydratase (DCH) hydrates the fluorocyclohexa-1,5-diene-1-carbonyl-CoA isomers to a mixture of the stable 2-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA and the unstable alpha-fluorohydrin 6-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA. The latter spontaneously decomposes to HF and 6-oxo-cyclohexa-1-ene-1-carbonyl-CoA, a common intermediate of the benzoyl-coenzyme A (BzCoA) degradation pathway. 6-Oxo-cyclohexa-1-ene-1-carbonyl-CoA hydrolase/hydratase catalyzes the defluorination of 2-fluoro-6-hydroxy-1-enoyl-CoA to 2-oxo-6-hydroxy-1-enoyl-CoA and HF again via water addition to an fluoro-enoyl-CoA functionality
physiological function
-
the enzyme is involved in the biodegradation of the environmentally hazardous fluoroaromatics. The 1,5-dienoyl-CoA hydratase (DCH) hydrates the fluorocyclohexa-1,5-diene-1-carbonyl-CoA isomers to a mixture of the stable 2-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA and the unstable alpha-fluorohydrin 6-fluoro-6-hydroxycyclohexa-1-ene-1-carbonyl-CoA. The latter spontaneously decomposes to HF and 6-oxo-cyclohexa-1-ene-1-carbonyl-CoA, a common intermediate of the benzoyl-coenzyme A (BzCoA) degradation pathway. 6-Oxo-cyclohexa-1-ene-1-carbonyl-CoA hydrolase/hydratase catalyzes the defluorination of 2-fluoro-6-hydroxy-1-enoyl-CoA to 2-oxo-6-hydroxy-1-enoyl-CoA and HF again via water addition to an fluoro-enoyl-CoA functionality
-
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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).
The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). A0A1H5S5L8_9RHOO
258
0
27763
TrEMBL
Mitochondrion (Reliability: 4)
D3RXI0_FERPA
Ferroglobus placidus (strain DSM 10642 / AEDII12DO)
252
0
28129
TrEMBL
-
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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
29900
-
4 * 30000, SDS-PAGE of purified His-tag labeled protein, 4 * 29900, calculated mass of the His-tag labeled protein, native mass by gel filtration
30000
30400
30000
-
2 * 30000, SDS-PAGE of purified His-tag labeled protein, 2 * 30400, calculated mass of the His-tag labeled protein, native mass by Ferguson blot analysis
30000
-
3 * 30000, SDS-PAGE of purified His-tag labeled protein, 3 * 30400, calculated mass of the His-tag labeled protein, native mass by gel filtration
30000
-
4 * 30000, SDS-PAGE of purified His-tag labeled protein, 4 * 29900, calculated mass of the His-tag labeled protein, native mass by gel filtration
30400
-
2 * 30000, SDS-PAGE of purified His-tag labeled protein, 2 * 30400, calculated mass of the His-tag labeled protein, native mass by Ferguson blot analysis
30400
-
3 * 30000, SDS-PAGE of purified His-tag labeled protein, 3 * 30400, calculated mass of the His-tag labeled protein, native mass by gel filtration
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SUBUNIT
ORGANISM
UNIPROT
COMMENTARY
LITERATURE
dimer
tetramer
-
4 * 30000, SDS-PAGE of purified His-tag labeled protein, 4 * 29900, calculated mass of the His-tag labeled protein, native mass by gel filtration
trimer
-
3 * 30000, SDS-PAGE of purified His-tag labeled protein, 3 * 30400, calculated mass of the His-tag labeled protein, native mass by gel filtration
dimer
-
2 * 30000, SDS-PAGE of purified His-tag labeled protein, 2 * 30400, calculated mass of the His-tag labeled protein, native mass by Ferguson blot analysis
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PURIFICATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
recombinant His6-tagged enzyme from Escherichia coli strain MC4100 by nickel affinity chromatography and desalting gel filtration
recombinant protein using His-tag
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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed as His-tag fusion protein in Escherichia coli BL21(DE3)pLysS cells
gene dch, recombinant expression of C-terminally His6-tagged enzyme in Escherichia coli strain MC4100
expressed as His-tag fusion protein in Escherichia coli BL21(DE3)pLysS cells
-
expressed as His-tag fusion protein in Escherichia coli BL21(DE3)pLysS cells
-
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Harwood, C.S.; Gibson, J.
Shedding light on anaerobic benzene ring degradation: a process unique to prokaryotes?
J. Bacteriol.
179
301-309
1997
Aromatoleum evansii, Thauera aromatica
brenda
Koch, J.; Eisenreich, W.; Bacher, A.; Fuchs, G.
Products of enzymatic reduction of benzoyl-CoA, a key reaction in anaerobic aromatic metabolism
Eur. J. Biochem.
211
649-661
1993
Aromatoleum evansii
brenda
Boll, M.; Laempe, D.; Eisenreich, W.; Bachers, A.; Mittelberger, T.; Heinze, J.; Fuchs, G.
Nonaromatic products from anoxic conversion of benzoyl-CoA with benzoyl-CoA reductase and cyclohexa-1,5-diene-1-carbonyl-CoA hydratase
J. Biol. Chem.
275
21889-21895
2000
Thauera aromatica
brenda
Lampe, D.; Eisenreich, W.; Bacher, A.; Fuchs, G.
Cyclohexa-1,5-diene-1-carboxyl-CoA hydratase, an enzyme involved in anaerobic metabolism of benzoyl-CoA in the denitrifying bacterium Thauera aromatica
Eur. J. Biochem.
255
618-627
1998
Thauera aromatica
brenda
Peters, F.; Shinoda, Y.; McInerney, M.J.; Boll, M.
Cyclohexa-1,5-diene-1-carbonyl-coenzyme A (CoA) hydratases of Geobacter metallireducens and Syntrophus aciditrophicus: Evidence for a common benzoyl-CoA degradation pathway in facultative and strict anaerobes
J. Bacteriol.
189
1055-1060
2007
Desulfococcus multivorans, Geobacter metallireducens, Syntrophus aciditrophicus
brenda
Thiele, B.; Rieder, O.; Golding, B.T.; Mueller, M.; Boll, M.
Mechanism of enzymatic Birch reduction: stereochemical course and exchange reactions of benzoyl-CoA reductase
J. Am. Chem. Soc.
130
14050-14051
2008
Thauera aromatica (o87873)
brenda
Schmid, G.; Rene, S.B.; Boll, M.
Enzymes of the benzoyl-coenzyme A degradation pathway in the hyperthermophilic archaeon Ferroglobus placidus
Environ. Microbiol.
17
3289-3300
2015
Ferroglobus placidus (D3RXI0), Ferroglobus placidus, Ferroglobus placidus DSM 10642 (D3RXI0)
brenda
Tiedt, O.; Mergelsberg, M.; Eisenreich, W.; Boll, M.
Promiscuous defluorinating enoyl-CoA hydratases/hydrolases allow for complete anaerobic degradation of 2-fluorobenzoate
Front. Microbiol.
8
2579-2589
2017
Thauera aromatica (o87873), Thauera aromatica K172 (o87873)
brenda
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Release 2026.1 (March 2026)
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