Information on EC - hydroxydechloroatrazine ethylaminohydrolase

for references in articles please use BRENDA:EC3.5.4.43
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IUBMB Comments
Contains Zn2+. This bacterial enzyme is involved in degradation of the herbicide atrazine. The enzyme has a broad substrate range, and requires a monohydroxylated s-triazine ring with a minimum of one primary or secondary amine substituent and either a chloride or amine leaving group. It catalyses both deamination and dechlorination reactions.
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The expected taxonomic range for this enzyme is: Bacteria, Archaea, Eukaryota
adenosine aminohydrolase 3, artB, AtzB, FRAAL1473, FraEuI1c_5875, HAEA, hydroxyatrazine ethylaminohydrolase, Hydroxyatrazine hydrolase, hydroxyatrazine N-ethylaminohydrolase, More, more
hydroxyatrazine + H2O = N-isopropylammelide + ethylamine
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Involved in a pathway by which the herbicide atrazine, 2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-triazine, is degraded in bacteria via N-isopropylammelide, 2,4-dihydroxy-6-(isopropylamino)-1,3,5-triazine
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