Disease on EC 3.4.22.43 - cathepsin V

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Alopecia
Evaluation of the CTSL2 Gene as a Candidate Gene For Alopecia X in Pomeranians and Keeshonden.
Arthritis
Polymorphisms in the cathepsin L2 (CTSL2) gene show association with type 1 diabetes and early-onset myasthenia gravis.
Arthritis, Juvenile
Polymorphisms in the cathepsin L2 (CTSL2) gene show association with type 1 diabetes and early-onset myasthenia gravis.
Arthritis, Rheumatoid
Polymorphisms in the cathepsin L2 (CTSL2) gene show association with type 1 diabetes and early-onset myasthenia gravis.
Atherosclerosis
Solution phase synthesis of a combinatorial library of chalcones and flavones as potent cathepsin V inhibitors.
Autoimmune Diseases
Polymorphisms in the cathepsin L2 (CTSL2) gene show association with type 1 diabetes and early-onset myasthenia gravis.
Breast Neoplasms
An exploratory study of host polymorphisms in genes that clinically characterize breast cancer tumors and pretreatment cognitive performance in breast cancer survivors.
Carcinoma, Ductal
Prognostic significance of cathepsin V (CTSV/CTSL2) in breast ductal carcinoma in situ.
Carcinoma, Intraductal, Noninfiltrating
Prognostic significance of cathepsin V (CTSV/CTSL2) in breast ductal carcinoma in situ.
Dermatitis, Atopic
The cystatin M / E-controlled pathway of skin barrier formation: expression of its key components in psoriasis and atopic dermatitis.
Endometrial Neoplasms
Expression of cysteine protease cathepsin L is increased in endometrial cancer and correlates with expression of growth regulatory genes.
Keratoconus
Increased levels of catalase and cathepsin V/L2 but decreased TIMP-1 in keratoconus corneas: evidence that oxidative stress plays a role in this disorder.
Lung Neoplasms
Manipulating substrate and pH in zymography protocols selectively distinguishes cathepsins K, L, S, and V activity in cells and tissues.
Myasthenia Gravis
Cathepsin V is involved in the degradation of invariant chain in human thymus and is overexpressed in myasthenia gravis.
Neoplasm Metastasis
Determination of cathepsin V activity and intracellular trafficking by N-glycosylation.
Neoplasms
An exploratory study of host polymorphisms in genes that clinically characterize breast cancer tumors and pretreatment cognitive performance in breast cancer survivors.
CTSL2 is a pro-apoptotic target of E2F1 and a modulator of histone deacetylase inhibitor and DNA damage-induced apoptosis.
Determination of cathepsin V activity and intracellular trafficking by N-glycosylation.
Expression of cysteine protease cathepsin L is increased in endometrial cancer and correlates with expression of growth regulatory genes.
Manipulating substrate and pH in zymography protocols selectively distinguishes cathepsins K, L, S, and V activity in cells and tissues.
Neuroblastoma
Human cathepsin V protease participates in the production of enkephalin and NPY neurotransmitters.
Placenta Accreta
Possible Association between Cathepsin V and the Development of Placenta Accreta Spectrum Disorders.
Psoriasis
The cystatin M / E-controlled pathway of skin barrier formation: expression of its key components in psoriasis and atopic dermatitis.
Scleroderma, Systemic
Decreased cathepsin V expression due to Fli1 deficiency contributes to the development of dermal fibrosis and proliferative vasculopathy in systemic sclerosis.
Vascular Diseases
l-Homocysteine-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinaemia.