Disease on EC 3.2.2.6 - ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenoma
The expression of messenger RNA for ADP-ribosyl cyclase in aldosterone-producing adenomas.
adenylate cyclase deficiency
An enzymatic alteration secondary to adenylyl cyclase deficiency in the cr-1 (crisp) mutant of Neurospora crassa: nicotinamide adenine dinucleotide (phosphate) glycohydrolase overproduction.
Anemia
Erythrocyte CD38 as a prognostic marker in cancer.
Brain Injuries
Perinatal hypoxic-ischemic brain injury affects the glutamatergic signal transduction coupled with neuronal ADP-ribosyl cyclase activity.
Cardiomegaly
Inhibition of ADP-ribosyl cyclase attenuates angiotensin II-induced cardiac hypertrophy.
Diabetic Nephropathies
Role of kidney ADP-ribosyl cyclase in diabetic nephropathy.
Glioma
Muscarinic receptor-mediated dual regulation of ADP-ribosyl cyclase in NG108-15 neuronal cell membranes.
Signal transduction from bradykinin, angiotensin, adrenergic and muscarinic receptors to effector enzymes, including ADP-ribosyl cyclase.
Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic glutamate receptors in retina, cervical superior ganglion and NG108-15 cells.
Lupus Erythematosus, Systemic
CD38 polymorphisms in Spanish patients with systemic lupus erythematosus.
Myocardial Ischemia
Myocardial ischemia and reperfusion reduce the levels of cyclic ADP-ribose in rat myocardium.
Neoplasms
cADP-ribose/ryanodine channel/Ca2+-release signal transduction pathway in mesangial cells.
Changes in NAD/ADP-ribose metabolism in rectal cancer.
Cyclic ADP-ribose as a potential second messenger for neuronal Ca2+ signaling.
Erythrocyte CD38 as a prognostic marker in cancer.
Nervous System Diseases
Role of ADP-ribosyl cyclase in the pathogenesis of neurological disorders after coronary artery bypass surgery and experimental ischemia.
Neuroblastoma
Bradykinin activates ADP-ribosyl cyclase in neuroblastoma cells: intracellular concentration decrease in NAD and increase in cyclic ADP-ribose.
Muscarinic receptor-mediated dual regulation of ADP-ribosyl cyclase in NG108-15 neuronal cell membranes.
Signal transduction from bradykinin, angiotensin, adrenergic and muscarinic receptors to effector enzymes, including ADP-ribosyl cyclase.
Subtype-specific coupling with ADP-ribosyl cyclase of metabotropic glutamate receptors in retina, cervical superior ganglion and NG108-15 cells.
Rectal Neoplasms
Changes in NAD/ADP-ribose metabolism in rectal cancer.
Tuberculosis
[NAD(P)-glycohydrolase in tuberculosis bacteria. A contribution to the mechanism of action INH]
Uterine Cervical Neoplasms
Increase of NAD glycohydrolase activity in uterine cervix cancers is caused by infiltration of lymphocytes.
Whooping Cough
Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger.
Abscisic acid is an endogenous stimulator of insulin release from human pancreatic islets with cyclic ADP ribose as second messenger.
Recombinant human serotonin 5A receptors stably expressed in C6 glioma cells couple to multiple signal transduction pathways.