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Information on EC 2.7.7.61 - citrate lyase holo-[acyl-carrier protein] synthase

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IUBMB Comments
The gamma-subunit of EC 4.1.3.6, citrate (pro-3S) lyase, serves as an acyl-carrier protein (ACP) and contains the prosthetic group 2'-(5-triphosphoribosyl)-3'-dephospho-CoA [1,3]. Synthesis and attachment of the prosthetic group requires the concerted action of this enzyme and EC 2.4.2.52, triphosphoribosyl-dephospho-CoA synthase . In the enzyme from Escherichia coli, the prosthetic group is attached to serine-14 of the ACP via a phosphodiester bond.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase, 2'-(5'-triphosphoribosyl)-3'-dephospho-CoA:apo-ACP 2'-(5'-phosphoribosyl)-3'-dephospho-CoA transferase, 2'-(5'-triphosphoribosyl)-3'-dephospho-CoA:apo-acyl-carrier protein phosphoribosyl-dephospho-coenzyme A transferase, 2'-(5'-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase, apo-citrate lyase phosphoribosyl dephospho-CoA transferase, citrate lyase holo-ACP synthetase, CitX, holo-ACP synthase, holo-citrate lyase synthase, malonate decarboxylase holo-ACP synthetase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2'-(5-triphosphoribosyl)-3'-dephospho-CoA + apo-[citrate (pro-3S)-lyase] = diphosphate + holo-[citrate (pro-3S)-lyase]
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PATHWAY SOURCE
PATHWAYS
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