Disease on EC 2.7.1.23 - NAD+ kinase
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Adenocarcinoma
NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma.
Endometrial Neoplasms
Distinct clinical and genetic mutation characteristics in sporadic and Lynch syndrome-associated endometrial cancer in a Chinese population.
Hyperlysinemias
Clinical heterogeneity of mitochondrial NAD kinase deficiency caused by a NADK2 start loss variant.
Hyperlysinemias
Mitochondrial NADP(H) deficiency due to a mutation in NADK2 causes dienoyl-CoA reductase deficiency with hyperlysinemia.
Hypersensitivity
NADK2, an Arabidopsis chloroplastic NAD kinase, plays a vital role in both chlorophyll synthesis and chloroplast protection.
Hypersensitivity
NADK3, a novel cytoplasmic source of NADPH, is required under conditions of oxidative stress and modulates abscisic acid responses in Arabidopsis.
nad+ kinase deficiency
Clinical heterogeneity of mitochondrial NAD kinase deficiency caused by a NADK2 start loss variant.
Neoplasms
Enhanced degradation of dihydrofolate reductase through inhibition of NAD kinase by nicotinamide analogs.
Neoplasms
Extramedullary relapse of multiple myeloma defined as the highest risk group based on deregulated gene expression data.
Nervous System Malformations
Lysine Restriction and Pyridoxal Phosphate Administration in a NADK2 Patient.
Staphylococcal Infections
From Substrate to Fragments to Inhibitor Active In Vivo against Staphylococcus aureus.
Tuberculosis
A novel fold revealed by Mycobacterium tuberculosis NAD kinase, a key allosteric enzyme in NADP biosynthesis.
Tuberculosis
Characterization of Mycobacterium tuberculosis NAD kinase: functional analysis of the full-length enzyme by site-directed mutagenesis.
Tuberculosis
Crystallization and preliminary X-ray analysis of NAD kinase from Mycobacterium tuberculosis H37Rv.
Tuberculosis
Crystallographic studies of Mycobacterium tuberculosis polyphosphate/ATP-NAD kinase complexed with NAD.
Tuberculosis
Establishment of a mass-production system for NADP using bacterial inorganic polyphosphate/ATP-NAD kinase.
Tuberculosis
First archaeal inorganic polyphosphate/ATP-dependent NAD kinase, from hyperthermophilic archaeon Pyrococcus horikoshii: cloning, expression, and characterization.
Tuberculosis
Inorganic Polyphosphate/ATP-NAD kinase of Micrococcus flavus and Mycobacterium tuberculosis H37Rv.
Tuberculosis
NAD-binding mode and the significance of intersubunit contact revealed by the crystal structure of Mycobacterium tuberculosis NAD kinase-NAD complex.
Tuberculosis
Overexpression, purification, and characterization of ATP-NAD kinase of Sphingomonas sp. A1.
Tuberculosis
Probing binding requirements of NAD kinase with modified substrate (NAD) analogues.
Tuberculosis
Selective inhibition of nicotinamide adenine dinucleotide kinases by dinucleoside disulfide mimics of nicotinamide adenine dinucleotide analogues.
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