BRENDA Home
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
IUBMB CommentsThe enzyme, characterized from the cyanobacterium Fischerella ambigua UTEX 1903, participates in the biosynthesis of hapalindole-type alkaloids.
The expected taxonomic range for this enzyme is: Fischerella ambigua
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
famD2
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
geranyl diphosphate + 3-[(Z)-2-isocyanoethenyl]-1H-indole = 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole + diphosphate
-
-
-
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
geranyl-diphosphate:3-[(Z)-2-isocyanoethenyl]-1H-indole geranyltransferase
The enzyme, characterized from the cyanobacterium Fischerella ambigua UTEX 1903, participates in the biosynthesis of hapalindole-type alkaloids.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3-[(E)-2-isocyanoethenyl]-1H-indole + dimethylallyl diphosphate
3-[(E)-2-isocyanoethenyl]-2-(3-methylbut-2-en-1-yl)-1H-indole + 3-[(E)-2-isocyanoethenyl]-3-(3-methylbut-2-en-1-yl)-3H-indole
3-[(E)-2-isocyanoethenyl]-1H-indole + geranyl diphosphate
2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-1H-indole + 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-3H-indole
3-[(E)-2-isocyanoethenyl]-1H-indole + dimethylallyl diphosphate
3-[(E)-2-isocyanoethenyl]-2-(3-methylbut-2-en-1-yl)-1H-indole + 3-[(E)-2-isocyanoethenyl]-3-(3-methylbut-2-en-1-yl)-3H-indole
-
-
-
?
3-[(E)-2-isocyanoethenyl]-1H-indole + dimethylallyl diphosphate
3-[(E)-2-isocyanoethenyl]-2-(3-methylbut-2-en-1-yl)-1H-indole + 3-[(E)-2-isocyanoethenyl]-3-(3-methylbut-2-en-1-yl)-3H-indole
-
-
-
-
?
3-[(E)-2-isocyanoethenyl]-1H-indole + dimethylallyl diphosphate
3-[(E)-2-isocyanoethenyl]-2-(3-methylbut-2-en-1-yl)-1H-indole + 3-[(E)-2-isocyanoethenyl]-3-(3-methylbut-2-en-1-yl)-3H-indole
-
-
-
-
?
3-[(E)-2-isocyanoethenyl]-1H-indole + dimethylallyl diphosphate
3-[(E)-2-isocyanoethenyl]-2-(3-methylbut-2-en-1-yl)-1H-indole + 3-[(E)-2-isocyanoethenyl]-3-(3-methylbut-2-en-1-yl)-3H-indole
-
-
-
?
3-[(E)-2-isocyanoethenyl]-1H-indole + geranyl diphosphate
2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-1H-indole + 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-3H-indole
preferred reaction
-
-
?
3-[(E)-2-isocyanoethenyl]-1H-indole + geranyl diphosphate
2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-1H-indole + 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-3H-indole
-
preferred reaction
-
-
?
3-[(E)-2-isocyanoethenyl]-1H-indole + geranyl diphosphate
2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-1H-indole + 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-3H-indole
-
preferred reaction
-
-
?
3-[(E)-2-isocyanoethenyl]-1H-indole + geranyl diphosphate
2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-1H-indole + 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-3H-indole
preferred reaction
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3-[(E)-2-isocyanoethenyl]-1H-indole + geranyl diphosphate
2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-1H-indole + 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-3H-indole
3-[(E)-2-isocyanoethenyl]-1H-indole + geranyl diphosphate
2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-1H-indole + 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-3H-indole
preferred reaction
-
-
?
3-[(E)-2-isocyanoethenyl]-1H-indole + geranyl diphosphate
2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-1H-indole + 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-3H-indole
-
preferred reaction
-
-
?
3-[(E)-2-isocyanoethenyl]-1H-indole + geranyl diphosphate
2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-1H-indole + 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-3H-indole
-
preferred reaction
-
-
?
3-[(E)-2-isocyanoethenyl]-1H-indole + geranyl diphosphate
2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-1H-indole + 3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-[(Z)-2-isocyanoethenyl]-3H-indole
preferred reaction
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
-
-
-
brenda
-
UniProt
brenda
-
-
-
brenda
-
UniProt
brenda
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
V5TDZ4_FISAU
Fischerella ambigua (strain UTEX 1903)
309
0
35115
TrEMBL
other Location (Reliability: 5)
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
expressed in Escherichia coli BL21(DE3) cells
-
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Li, S.; Lowell, A.N.; Yu, F.; Raveh, A.; Newmister, S.A.; Bair, N.; Schaub, J.M.; Williams, R.M.; Sherman, D.H.
Hapalindole/ambiguine biogenesis is mediated by a cope rearrangement, C-C bond-forming cascade
J. Am. Chem. Soc.
137
15366-15369
2015
Fischerella ambigua, Fischerella ambigua UTEX 1903
brenda
Wang, J.; Chen, C.C.; Yang, Y.; Liu, W.; Ko, T.P.; Shang, N.; Hu, X.; Xie, Y.; Huang, J.W.; Zhang, Y.; Guo, R.T.
Structural insight into a novel indole prenyltransferase in hapalindole-type alkaloid biosynthesis
Biochem. Biophys. Res. Commun.
495
1782-1788
2018
Fischerella ambigua (V5TDZ4), Fischerella ambigua UTEX 1903 (V5TDZ4)
brenda
Select items on the left to see more content.
html completed