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Information on EC 2.4.2.44 - S-methyl-5'-thioinosine phosphorylase

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EC Tree
     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.44 S-methyl-5'-thioinosine phosphorylase
IUBMB Comments
No activity with S-methyl-5'-thioadenosine. The catabolism of of 5'-methylthioadenosine in Pseudomonas aeruginosa involves deamination to S-methyl-5'-thioinosine (EC 3.5.4.31, S-methyl-5'-thioadenosine deaminase) and phosphorolysis to hypoxanthine .
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The expected taxonomic range for this enzyme is: Pseudomonas aeruginosa
Synonyms
methylthioinosine phosphorylase, MTI phosphorylase, MTIP, PA3004, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-methyl-5'-thioinosine + phosphate = hypoxanthine + S-methyl-5-thio-alpha-D-ribose 1-phosphate
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