EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.4.2.44 | 5'-methylthioinosine + phosphate |
- |
Pseudomonas aeruginosa |
hypoxanthine + 5-methylthio-alpha-D-ribose 1-phosphate |
- |
? |
2.4.2.44 | adenosine + phosphate |
weak substrate |
Pseudomonas aeruginosa |
adenine + alpha-D-ribose 1-phosphate |
- |
? |
2.4.2.44 | adenosine + phosphate |
- |
Pseudomonas aeruginosa |
adenine + D-ribose 1-phosphate |
- |
? |
2.4.2.44 | inosine + phosphate |
the catalytic efficiency (kcat/Km) for S-methyl-5'-thioinosine is 290 times larger than for inosine |
Pseudomonas aeruginosa |
hypoxanthine + alpha-D-ribose 1-phosphate |
- |
? |
2.4.2.44 | inosine + phosphate |
- |
Pseudomonas aeruginosa |
hypoxanthine + D-ribose 1-phosphate |
- |
? |
2.4.2.44 | more |
S-methyl-5'-thioadenosine is not a substrate |
Pseudomonas aeruginosa |
? |
- |
? |
2.4.2.44 | S-methyl-5'-thioinosine + phosphate |
the enzyme is involved in catabolism of 5'-methylthioadenosine in Pseudomonas aeruginosa. S-Methyl-5'-thioadenosine is converted to S-methyl-5'-thioinosine and hypoxanthine but not to adenine |
Pseudomonas aeruginosa |
hypoxanthine + S-methyl-5-thio-alpha-D-ribose 1-phosphate |
- |
? |
2.4.2.44 | S-methyl-5'-thioinosine + phosphate |
the methylthio group of S-methyl-5'-thioinosine is important for both substrate binding and catalysis |
Pseudomonas aeruginosa |
hypoxanthine + S-methyl-5-thio-alpha-D-ribose 1-phosphate |
- |
? |