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Information on EC 2.1.1.49 - amine N-methyltransferase

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.49 amine N-methyltransferase
IUBMB Comments
An enzyme of very broad specificity; many primary, secondary and tertiary amines can act as acceptors, including tryptamine, aniline, nicotine and a variety of drugs and other xenobiotics.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
aromatic alkylamine-N-methyltransferase, arylamine N-methyltransferase, methyltransferase, tryptamine, nicotine N-methyltransferase, tryptamine methyltransferase, tryptamine N-methyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine
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PATHWAY SOURCE
PATHWAYS
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