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Information on EC 2.1.1.323 - (-)-pluviatolide 4-O-methyltransferase

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EC Tree
     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.323 (-)-pluviatolide 4-O-methyltransferase
IUBMB Comments
The enzyme, characterized from the plant Sinopodophyllum hexandrum, is involved in the biosynthetic pathway of podophyllotoxin, a non-alkaloid toxin lignan whose derivatives are important anticancer drugs.
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The expected taxonomic range for this enzyme is: Sinopodophyllum hexandrum
Synonyms
OMT3, pluviatolide 4-O-methyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl-L-methionine + (-)-pluviatolide = S-adenosyl-L-homocysteine + (-)-bursehernin
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