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Information on EC 1.3.1.90 - tRNA-dihydrouridine20a/20b synthase [NAD(P)+]

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IUBMB Comments
A flavoenzyme. The enzyme specifically modifies uracil20a and uracil20b in tRNA.
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The enzyme appears in viruses and cellular organisms
Reaction Schemes
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5,6-dihydrouracil20a in tRNA
+
NAD(P)+
=
uracil20a in tRNA
+
NAD(P)H
+
H+
5,6-dihydrouracil20a in tRNA
+
=
uracil20a in tRNA
+
+
5,6-dihydrouracil20b in tRNA
+
NAD(P)+
=
uracil20b in tRNA
+
NAD(P)H
+
H+
5,6-dihydrouracil20b in tRNA
+
=
uracil20b in tRNA
+
+
Synonyms
Dus4p, tRNA-dihydrouridine synthase 4, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
5,6-dihydrouracil20a in tRNA + NAD(P)+ = uracil20a in tRNA + NAD(P)H + H+
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5,6-dihydrouracil20b in tRNA + NAD(P)+ = uracil20b in tRNA + NAD(P)H + H+
show the reaction diagram
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