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IUBMB CommentsActs in the reverse direction to form part of the 3-methylquinoline degradation pathway in bacteria.
The expected taxonomic range for this enzyme is: Comamonas testosteroni
Synonyms
5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline:NAD+ oxidoreductase,
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5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline:NAD+ oxidoreductase
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5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+ = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH + H+
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5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline:NAD+ oxidoreductase
Acts in the reverse direction to form part of the 3-methylquinoline degradation pathway in bacteria.
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5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
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5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
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degradation pathway for 3-methylquinoline
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r
5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
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r
5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
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degradation pathway for 3-methylquinoline
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r
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5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
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degradation pathway for 3-methylquinoline
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r
5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH
5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
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degradation pathway for 3-methylquinoline
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r
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5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline is unstable in presence of air
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Schach, S.; Schwarz, G.; Fetzner, S.; Lingens, F.
Microbial metabolism of quinoline and related compounds. XVII. Degradation of 3-methylquinoline by Comamonas testosteroni 63
Biol. chem.
374
175 - 181
1993
Comamonas testosteroni, Comamonas testosteroni 63
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1.3.1.65 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase
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