Information on EC 1.14.14.72 - drimenol monooxygenase

for references in articles please use BRENDA:EC1.14.14.72
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The expected taxonomic range for this enzyme is: Persicaria hydropiper

EC NUMBER
COMMENTARY hide
1.14.14.72
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RECOMMENDED NAME
GeneOntology No.
drimenol monooxygenase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
drimenol + [reduced NADPH-hemoprotein reductase] + O2 = drimendiol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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-
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SYSTEMATIC NAME
IUBMB Comments
drimenol,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (drimendiol forming)
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
W0FKI0
UniProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
W0FKI0
coexpression of drimenol synthase with drimenol oxidase DOX1 in yeast yields drimendiol, the 12-hydroxylation product of drimenol, as a major product, and cinnamolide. Upon coexpression of drimenol synthase with drimenol oxidase DOX1 in Nicotiana benthamiana leaves, drimenol is almost completely converted into cinnamolide and several additional drimenol derivatives are observed
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
drimenol + [reduced NADPH—hemoprotein reductase] + O2
drimendiol + [oxidized NADPH—hemoprotein reductase] + H2O
show the reaction diagram
W0FKI0
-
-
-
?
additional information
?
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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
cytochrome P450
W0FKI0
-
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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.011
drimenol
W0FKI0
pH 7.5, 25°C
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
?
W0FKI0
x * 56149, calculated