Information on EC 1.14.14.67 - 11-hydroxysugiol 20-monooxygenase

for references in articles please use BRENDA:EC1.14.14.67
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Select one or more organisms in this record:


The expected taxonomic range for this enzyme is: Salvia miltiorrhiza

top print hide
EC NUMBER
COMMENTARY hide
1.14.14.67
-
top print hide
RECOMMENDED NAME
GeneOntology No.
11-hydroxysugiol 20-monooxygenase
-
top print hide
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
11-hydroxysugiol + [reduced NADPH-hemoprotein reductase] + O2 = 11,20-dihydroxysugiol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
-
top print hide
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
Diterpenoid biosynthesis
-
-
Biosynthesis of secondary metabolites
-
-
top print hide
SYSTEMATIC NAME
IUBMB Comments
11-hydroxysugiol,[reduced NADPH-hemoprotein reductase]:oxygen oxidoreductase (11,20-dihydroxysugiol forming)
-
top
top print hide
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
top print hide
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
11-hydroxyferruginol + [reduced NADPH-hemoprotein reductase] + O2
11,20-dihydroxyferruginol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
11-hydroxysugiol + [reduced NADPH-hemoprotein reductase] + O2
11,20-dihydroxysugiol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
additional information
?
-
enzyme hydroxylates 11-hydroxyferruginol and 11-hydroxysugiol at C-20 to give 11,20-dihydroxyferruginal and 11,20-dihydroxysugiol
-
-
-
top print hide
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
top print hide
Crystallization/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
homology modeling of structure
top print hide
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expression in Saccharomyces cerevisiae
top
top
top
LINKS TO OTHER DATABASES (specific for EC-Number 1.14.14.67)
ExplorEnz
ExPASy
KEGG
MetaCyc
SABIO-RK
NCBI: PubMed, Protein, Nucleotide, Structure, Genome, OMIM
IUBMB Enzyme Nomenclature
PROSITE Database of protein families and domains
InterPro (database of protein families, domains and functional sites)