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Information on EC 1.14.14.169 - eupatolide synthase

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The enzyme appears in viruses and cellular organisms
Reaction Schemes
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Synonyms
CYP71DD6, HaES, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
6alpha,8beta-dihydroxygermacra-1(10),4,11(13)-trien-12-oate = eupatolide + H2O
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(1c), spontaneous
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8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH-hemoprotein reductase] + O2 = 6alpha,8beta-dihydroxygermacra-1(10),4,11(13)-trien-12-oate + [oxidized NADPH-hemoprotein reductase] + H2O
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(1a)
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8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH-hemoprotein reductase] + O2 = eupatolide + [oxidized NADPH-hemoprotein reductase] + 2 H2O
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overall reaction
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