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EC 1.16.3.2 Details

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EC number

1.16.3.2

Accepted name

bacterial non-heme ferritin

Reaction

4 Fe(II) + O₂ + 6 H₂O = 4 [FeO(OH)] + 8 H⁺ (overall reaction);;(1a) 2 Fe(II) + O₂ + 4 H₂O = 2 [FeO(OH)] + 4 H⁺ + H₂O₂;;(1b) 2 Fe(II) + H₂O₂ + 2 H₂O = 2 [FeO(OH)] + 4 H⁺

Other name(s)

FtnA, HuHF

Systematic name

Fe(II):oxygen oxidoreductase ([FeO(OH)]core-producing)

Comment

Ferritins are intracellular iron-storage and detoxification proteins found in all kingdoms of life. They are formed from two subunits that co-assemble in various ratios to form a spherical protein shell. Thousands of mineralized iron atoms are stored within the core of the structure. The product of dioxygen reduction by the bacterial non-heme ferritin is hydrogen peroxide, which is consumed in a subsequent reaction.

History

created 2014

EC Tree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.2 Acting on the aldehyde or oxo group of donors

1.3 Acting on the CH-CH group of donors

1.4 Acting on the CH-NH₂ group of donors

1.5 Acting on the CH-NH group of donors

1.6 Acting on NADH or NADPH

1.7 Acting on other nitrogenous compounds as donors

1.8 Acting on a sulfur group of donors

1.9 Acting on a heme group of donors

1.10 Acting on diphenols and related substances as donors

1.11 Acting on a peroxide as acceptor

1.11.1 Peroxidases

1.11.2 Peroxygenases

1.12 Acting on hydrogen as donor

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.15 Acting on superoxide as acceptor

1.16 Oxidizing metal ions

1.16.1 With NAD⁺ or NADP⁺ as acceptor

1.16.3 With oxygen as acceptor

1.16.3.1 ferroxidase

1.16.3.2 bacterial non-heme ferritin

1.16.3.3 manganese oxidase

1.16.3.4 cuproxidase

1.16.5 With a quinone or similar compound as acceptor

1.16.8 With a flavin as acceptor

1.16.9 With a copper protein as acceptor

1.16.98 With other, known, physiological acceptors

1.16.99 With unknown physiological acceptors

1.17 Acting on CH or CH₂ groups

1.18 Acting on iron-sulfur proteins as donors

1.19 Acting on reduced flavodoxin as donor

1.20 Acting on phosphorus or arsenic in donors

1.21 Catalysing the reaction X-H + Y-H = X-Y

1.22 Acting on halogen in donors

1.22.1 With NAD⁺ or NADP⁺ as acceptor

1.23 Reducing C-O-C group as acceptor

1.97 Other oxidoreductases

1.98 Enzymes using H₂ as reductant (deleted subclass)

1.99 Other enzymes using O₂ as oxidant (deleted subclass)

1.99.1 Hydroxylases (now covered by EC 1.14)

1.99.1.1 created 1961, deleted 1965

1.99.1.2 created 1961, deleted 1965

1.99.1.3 created 1961, deleted 1965

1.99.1.4 created 1961, deleted 1965

1.99.1.5 created 1961, deleted 1965

1.99.1.6 created 1961, deleted 1965

1.99.1.7 created 1961, deleted 1965

1.99.1.8 created 1961, deleted 1965

1.99.1.9 created 1961, deleted 1965

1.99.1.10 created 1961, deleted 1965

1.99.1.11 created 1961, deleted 1965

1.99.1.12 created 1961, deleted 1965

1.99.1.13 created 1961, deleted 1965

1.99.1.14 created 1961, deleted 1965

1.99.2 Oxygenases (now covered by EC 1.13)