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EC 5.3.3.2 Details
EC number
5.3.3.2
Accepted name
isopentenyl-diphosphate Δ-isomerase
Reaction
3-methylbut-3-en-1-yl diphosphate = prenyl diphosphate
Other name(s)
isopentenylpyrophosphate Δ-isomerase,
methylbutenylpyrophosphate isomerase,
isopentenylpyrophosphate isomerase,
isopentenyl-diphosphate Δ3-Δ2-isomerase
Systematic name
3-methylbut-3-en-1-yl-diphosphate Δ3-Δ2-isomerase
CAS registry number
9033-27-6
Comment
The enzyme from Streptomyces sp. strain CL190 requires FMN and NAD(P)H as cofactors. Activity is reduced if FMN is replaced by FAD, but the enzyme becomes inactive when NAD(P)H is replaced by NAD+ or NADP+. That enzyme also requires Mg2+, Mn2+ or Ca2+ for activity.
History
created 1961, modified 2002
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