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EC 1.1.2.10 Details
EC number
1.1.2.10
Accepted name
lanthanide-dependent methanol dehydrogenase
Reaction
methanol + 2 oxidized cytochrome cL = formaldehyde + 2 reduced cytochrome cL
Other name(s)
XoxF,
XoxF-MDH,
Ce-MDH,
La3+-dependent MDH,
Ce3+-induced methanol dehydrogenase,
cerium dependent MDH
Systematic name
methanol:cytochrome cL oxidoreductase
Comment
Isolated from the bacterium Methylacidiphilum fumariolicum and many Methylobacterium species. Requires La3+, Ce3+, Pr3+ or Nd3+. The higher lanthanides show decreasing activity with Sm3+, Eu3+ and Gd3+. The lanthanide is coordinated by the enzyme and pyrroloquinoline quinone. Shows little activity with Ca2+, the required cofactor of EC 1.1.2.7, methanol dehydrogenase (cytochrome c).
History
created 2019
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