Any feedback?
Please rate this page
(ecexplorer.php)
(0/150)

BRENDA support

EC Explorer

[browse EC tree] - [search]
EC 3.1.4.41 Details
EC number
3.1.4.41
Accepted name
sphingomyelin phosphodiesterase D
Reaction
sphingomyelin + H2O = ceramide phosphate + choline
Other name(s)
sphingomyelinase D
Systematic name
sphingomyelin ceramide-phosphohydrolase
CAS registry number
54992-31-3
Comment
Does not act on phosphatidylcholine, but hydrolyses 2-lysophosphatidylcholine to choline and 2-lysophosphatidate.
History
created 1978
back to top
EC Tree
1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.2 Acting on the aldehyde or oxo group of donors
1.3 Acting on the CH-CH group of donors
1.4 Acting on the CH-NH2 group of donors
1.5 Acting on the CH-NH group of donors
1.6 Acting on NADH or NADPH
1.7 Acting on other nitrogenous compounds as donors
1.8 Acting on a sulfur group of donors
1.9 Acting on a heme group of donors
1.10 Acting on diphenols and related substances as donors
1.11 Acting on a peroxide as acceptor
1.12 Acting on hydrogen as donor
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.1 With NADH or NADPH as one donor (deleted sub-subclass)
1.14.2 With ascorbate as one donor (deleted sub-subclass)
1.14.3 With reduced pteridine as one donor (deleted sub-subclass)
1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.17 With reduced ascorbate as one donor, and incorporation of one atom of oxygen into the other donor
1.14.18 With another compound as one donor, and incorporation of one atom of oxygen into the other donor
1.14.19 With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated
1.14.21 With NADH or NADPH as one donor, and the other dehydrogenated
1.14.99 Miscellaneous
1.15 Acting on superoxide as acceptor
1.16 Oxidizing metal ions
1.17 Acting on CH or CH2 groups
1.18 Acting on iron-sulfur proteins as donors
1.19 Acting on reduced flavodoxin as donor
1.20 Acting on phosphorus or arsenic in donors
1.21 Catalysing the reaction X-H + Y-H = X-Y
1.21.1 With NAD+ or NADP+ as acceptor
1.21.3 With oxygen as acceptor
1.21.4 With a disulfide as acceptor
1.21.98 With other, known, physiological acceptors
1.21.99 With unknown physiological acceptors
1.22 Acting on halogen in donors
1.23 Reducing C-O-C group as acceptor
1.97 Other oxidoreductases
1.98 Enzymes using H2 as reductant (deleted subclass)
1.99 Other enzymes using O2 as oxidant (deleted subclass)
2 Transferases
3 Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.2 Thioester hydrolases
3.1.3 Phosphoric-monoester hydrolases
3.1.4 Phosphoric-diester hydrolases
3.1.4.1 phosphodiesterase I
3.1.4.2 glycerophosphocholine phosphodiesterase
3.1.4.3 phospholipase C
3.1.4.4 phospholipase D
3.1.4.5 created 1961, deleted 1978
3.1.4.6 created 1961, deleted 1978
3.1.4.7 created 1961, deleted 1978
3.1.4.8 created 1961, transferred 1965 to EC 2.7.7.26, reinstated 1972, deleted 1978
3.1.4.9 created 1965, deleted 1978
3.1.4.10 created 1972, modified 1976, deleted 2002
3.1.4.11 phosphoinositide phospholipase C
3.1.4.12 sphingomyelin phosphodiesterase
3.1.4.13 serine-ethanolaminephosphate phosphodiesterase
3.1.4.14 [acyl-carrier-protein] phosphodiesterase
3.1.4.15 adenylyl-[glutamate—ammonia ligase] hydrolase
3.1.4.16 2′,3′-cyclic-nucleotide 2′-phosphodiesterase
3.1.4.17 3′,5′-cyclic-nucleotide phosphodiesterase
3.1.4.18 created 1972, deleted 1978
3.1.4.19 created 1972, deleted 1978
3.1.4.20 created 1972, deleted 1978
3.1.4.21 created 1972, deleted 1978
3.1.4.22 created 1972, deleted 1978
3.1.4.23 created 1972, deleted 1978
3.1.4.24 created 1972, deleted 1978
3.1.4.25 created 1972, deleted 1978
3.1.4.26 created 1972, deleted 1978
3.1.4.27 created 1972, deleted 1978
3.1.4.28 created 1972, deleted 1978
3.1.4.29 created 1972, deleted 1978
3.1.4.30 created 1972, deleted 1978
3.1.4.31 created 1972, deleted 1978
3.1.4.32 created 1972, deleted 1978
3.1.4.33 created 1972, deleted 1978
3.1.4.34 created 1972, deleted 1978
3.1.4.35 3′,5′-cyclic-GMP phosphodiesterase
3.1.4.36 created 1976, deleted 2002
3.1.4.37 2′,3′-cyclic-nucleotide 3′-phosphodiesterase
3.1.4.38 glycerophosphocholine cholinephosphodiesterase
3.1.4.39 alkylglycerophosphoethanolamine phosphodiesterase
3.1.4.40 CMP-N-acylneuraminate phosphodiesterase
3.1.4.41 sphingomyelin phosphodiesterase D
3.1.4.42 glycerol-1,2-cyclic-phosphate 2-phosphodiesterase
3.1.4.43 glycerophosphoinositol inositolphosphodiesterase
3.1.4.44 glycerophosphoinositol glycerophosphodiesterase
3.1.4.45 N-acetylglucosamine-1-phosphodiester α-N-acetylglucosaminidase
3.1.4.46 glycerophosphodiester phosphodiesterase
3.1.4.47 created 1989, deleted 2002
3.1.4.48 dolichylphosphate-glucose phosphodiesterase
3.1.4.49 dolichylphosphate-mannose phosphodiesterase
3.1.4.50 glycosylphosphatidylinositol phospholipase D
3.1.4.51 glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase
3.1.4.52 cyclic-guanylate-specific phosphodiesterase
3.1.4.53 3′,5′-cyclic-AMP phosphodiesterase
3.1.4.54 N-acetylphosphatidylethanolamine-hydrolysing phospholipase D
3.1.4.55 phosphoribosyl 1,2-cyclic phosphate phosphodiesterase
3.1.4.56 7,8-dihydroneopterin 2′,3′-cyclic phosphate phosphodiesterase
3.1.4.57 phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase
3.1.4.58 RNA 2′,3′-cyclic 3′-phosphodiesterase
3.1.4.59 cyclic-di-AMP phosphodiesterase
3.1.4.60 pApA phosphodiesterase
3.1.4.61 cyclic 2,3-diphosphoglycerate hydrolase
3.1.5 Triphosphoric-monoester hydrolases
3.1.6 Sulfuric-ester hydrolases
3.1.7 Diphosphoric-monoester hydrolases
3.1.8 Phosphoric-triester hydrolases
3.1.11 Exodeoxyribonucleases producing 5′-phosphomonoesters
3.1.12 Exodeoxyribonucleases producing 3′-phosphomonoesters
3.1.13 Exoribonucleases producing 5′-phosphomonoesters
3.1.14 Exoribonucleases producing 3'-phosphomonoesters
3.1.15 Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters
3.1.16 Exonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters
3.1.21 Endodeoxyribonucleases producing 5'-phosphomonoesters
3.1.22 Endodeoxyribonucleases producing 3'-phosphomonoesters
3.1.23 Site-specific endodeoxyribonucleases: cleavage is sequence specific (deleted sub-subclass)
3.1.24 Site specific endodeoxyribonucleases: cleavage is not sequence specific (deleted sub-subclass)
3.1.25 Site-specific endodeoxyribonucleases that are specific for altered bases
3.1.26 Endoribonucleases producing 5'-phosphomonoesters
3.1.27 Endoribonucleases producing 3'-phosphomonoesters
3.1.30 Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 5'-phosphomonoesters
3.1.31 Endoribonucleases that are active with either ribo- or deoxyribonucleic acids and produce 3'-phosphomonoesters
3.2 Glycosylases
3.3 Acting on ether bonds
3.4 Acting on peptide bonds (peptidases)
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.6 Acting on acid anhydrides
3.7 Acting on carbon-carbon bonds
3.8 Acting on halide bonds
3.9 Acting on phosphorus-nitrogen bonds
3.10 Acting on sulfur-nitrogen bonds
3.10.1 Acting on sulfur-nitrogen bonds (only sub-subclass identified to date)
3.11 Acting on carbon-phosphorus bonds
3.12 Acting on sulfur-sulfur bonds
3.13 Acting on carbon-sulfur bonds
4 Lyases
5 Isomerases
6 Ligases
7 Translocases