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EC 3.1.3.80 Details
EC number
3.1.3.80
Accepted name
2,3-bisphosphoglycerate 3-phosphatase
Reaction
2,3-bisphospho-D-glycerate + H2O = 2-phospho-D-glycerate + phosphate
Other name(s)
MIPP1, 2,3-BPG 3-phosphatase
Systematic name
2,3-bisphospho-D-glycerate 3-phosphohydrolase
Comment
This reaction is a shortcut in the Rapoport-Luebering shunt. It bypasses the reactions of EC 5.4.2.11/EC 5.4.2.12 [phosphoglycerate mutases (2,3-diphosphoglycerate-dependent and independent)] and directly forms 2-phospho-D-glycerate by removing the 3-phospho-group of 2,3-diphospho-D-glycerate [1]. The MIPP1 protein also catalyses the reaction of EC 3.1.3.62 (multiple inositol-polyphosphate phosphatase).
History
created 2010
EC Tree
3.1.3.30 created 1972, deleted 1992
3.1.3.61 created 1992, deleted 2002
3.1.3.65 created 1992, deleted 2002