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EC 3.6.1.12 Details
EC number
3.6.1.12
Accepted name
dCTP diphosphatase
Reaction
dCTP + H2O = dCMP + diphosphate
Other name(s)
DCTPP1 (gene name),
deoxycytidine-triphosphatase,
dCTPase,
dCTP pyrophosphatase,
deoxycytidine triphosphatase,
deoxy-CTPase
Systematic name
dCTP nucleotidohydrolase
CAS registry number
9024-87-7
Comment
The mammalian enzyme also displays weak activity against dTTP and dATP, but none against dGTP. Activity is highest with analogs including 5-iodo-dCTP and 5-methyl-dCTP.
History
created 1965
EC Tree
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