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EC 1.8.4.13 Details
EC number
1.8.4.13
Accepted name
L-methionine (S)-S-oxide reductase
Reaction
L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin
Other name(s)
fSMsr,
methyl sulfoxide reductase I and II,
acetylmethionine sulfoxide reductase,
methionine sulfoxide reductase,
L-methionine:oxidized-thioredoxin S-oxidoreductase,
methionine-S-oxide reductase,
free-methionine (S)-S-oxide reductase
Systematic name
L-methionine:thioredoxin-disulfide S-oxidoreductase
Comment
Requires NADPH [2]. The reaction occurs in the opposite direction to that given above. Dithiothreitol can replace reduced thioredoxin. L-Methionine (R)-S-oxide is not a substrate [see EC 1.8.4.14, L-methionine (R)-S-oxide reductase].
History
created 1984 as EC 1.8.4.5, part transferred 2006 to EC 1.8.4.13
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