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EC 1.8.4.6 Details
EC number
1.8.4.6
Accepted name
protein-methionine-S-oxide reductase
Reaction
protein L-methionine + thioredoxin disulfide = protein L-methionine S-oxide + thioredoxin
Other name(s)
methionine sulfoxide (protein) reductase,
methionine sulfoxide peptide reductase,
protein (methionine sulfoxide) reductase,
Met(O)-peptide reductase,
peptide methionine sulfoxide reductase,
protein-L-methionine:oxidized-thioredoxin S-oxidoreductase
Systematic name
protein-L-methionine:thioredoxin-disulfide S-oxidoreductase
CAS registry number
78206-57-2
Comment
Dithiothreitol, but not 2-mercaptoethanol, can replace a reduced thioredoxin in the reverse reaction. Does not act on free methionine (cf. EC 1.8.4.5 methionine-S-oxide reductase)
History
created 1984, deleted 2006
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