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EC 1.8.1.2 Details
EC number
1.8.1.2
Accepted name
assimilatory sulfite reductase (NADPH)
Reaction
hydrogen sulfide + 3 NADP+ + 3 H2O = sulfite + 3 NADPH + 3 H+
Other name(s)
sulfite reductase (NADPH), sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase, NADPH-sulfite reductase, NADPH-dependent sulfite reductase, H2S-NADP oxidoreductase, sulfite reductase (NADPH2), MET5 (gene name), MET10 (gene name), cysI (gene name), cysJ (gene name)
Systematic name
hydrogen-sulfide:NADP+ oxidoreductase
CAS registry number
9029-35-0
Comment
Contains siroheme, [4Fe-4S] cluster, FAD and FMN. The enzyme, which catalyses the six-electron reduction of sulfite to sulfide, is involved in sulfate assimilation in bacteria and yeast. Different from EC 1.8.99.5, dissimilatory sulfite reductase, which is involved in prokaryotic sulfur-based energy metabolism. cf. EC 1.8.7.1, assimilatory sulfite reductase (ferredoxin).
History
created 1961, modified 2015
EC Tree
1.6.8.1 created 1981, deleted 2002
1.6.8.2 created 1982, deleted 2002
1.8.1.1 created 1961, deleted 1972