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EC 1.8.1.19 Details

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EC number

1.8.1.19

Accepted name

sulfide dehydrogenase

Reaction

hydrogen sulfide + (sulfide)_n + NADP⁺ = (sulfide)_n+1 + NADPH + H⁺

Other name(s)

SuDH

Systematic name

hydrogen sulfide,polysulfide:NADP⁺ oxidoreductase

Comment

A iron-sulfur flavoprotein. In the archaeon Pyrococcus furiosus the enzyme is involved in the oxidation of NADPH which is produced in peptide degradation. The enzyme also catalyses the reduction of sulfur with lower activity.

History

created 2013

EC Tree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.2 With a cytochrome as acceptor

1.1.3 With oxygen as acceptor

1.1.4 With a disulfide as acceptor

1.1.5 With a quinone or similar compound as acceptor

1.1.7 With an iron-sulfur protein as acceptor

1.1.9 With a copper protein as acceptor

1.1.98 With other, known, physiological acceptors

1.1.99 With unknown physiological acceptors

1.2 Acting on the aldehyde or oxo group of donors

1.3 Acting on the CH-CH group of donors

1.4 Acting on the CH-NH₂ group of donors

1.5 Acting on the CH-NH group of donors

1.6 Acting on NADH or NADPH

1.7 Acting on other nitrogenous compounds as donors

1.8 Acting on a sulfur group of donors

1.8.1 With NAD⁺ or NADP⁺ as acceptor

1.8.1.1 created 1961, deleted 1972

1.8.1.2 assimilatory sulfite reductase (NADPH)

1.8.1.3 hypotaurine dehydrogenase

1.8.1.4 dihydrolipoyl dehydrogenase

1.8.1.5 2-oxopropyl-CoM reductase (carboxylating)

1.8.1.6 cystine reductase

1.8.1.7 glutathione-disulfide reductase

1.8.1.8 protein-disulfide reductase

1.8.1.9 thioredoxin-disulfide reductase

1.8.1.10 CoA-glutathione reductase

1.8.1.11 asparagusate reductase

1.8.1.12 trypanothione-disulfide reductase

1.8.1.13 bis-γ-glutamylcystine reductase

1.8.1.14 CoA-disulfide reductase

1.8.1.15 mycothione reductase

1.8.1.16 glutathione amide reductase

1.8.1.17 dimethylsulfone reductase

1.8.1.18 NAD(P)H sulfur oxidoreductase (CoA-dependent)

1.8.1.19 sulfide dehydrogenase

1.8.1.20 4,4′-dithiodibutanoate disulfide reductase

1.8.1.21 dissimilatory dimethyldisulfide reductase

1.8.2 With a cytochrome as acceptor

1.8.3 With oxygen as acceptor

1.8.4 With a disulfide as acceptor

1.8.5 With a quinone or similar compound as acceptor

1.8.6 With a nitrogenous group as acceptor (deleted sub-subclass)

1.8.7 With an iron-sulfur protein as acceptor

1.8.98 With other, known, physiological acceptors

1.8.99 With unknown physiological acceptors

1.8.99.1 assimilatory sulfite reductase

1.8.99.2 adenylyl-sulfate reductase

1.8.99.3 hydrogensulfite reductase

1.8.99.4 created 1999, deleted 2000

1.8.99.5 dissimilatory sulfite reductase

1.9 Acting on a heme group of donors

1.10 Acting on diphenols and related substances as donors

1.11 Acting on a peroxide as acceptor

1.12 Acting on hydrogen as donor

1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

1.15 Acting on superoxide as acceptor

1.16 Oxidizing metal ions

1.17 Acting on CH or CH₂ groups

1.18 Acting on iron-sulfur proteins as donors

1.19 Acting on reduced flavodoxin as donor

1.20 Acting on phosphorus or arsenic in donors

1.21 Catalysing the reaction X-H + Y-H = X-Y

1.21.1 With NAD⁺ or NADP⁺ as acceptor

1.21.3 With oxygen as acceptor

1.21.4 With a disulfide as acceptor

1.21.4.1 D-proline reductase

1.21.4.2 glycine reductase

1.21.4.3 sarcosine reductase

1.21.4.4 betaine reductase

1.21.4.5 tetrachlorohydroquinone reductive dehalogenase

1.21.98 With other, known, physiological acceptors

1.21.99 With unknown physiological acceptors

1.22 Acting on halogen in donors

1.23 Reducing C-O-C group as acceptor

1.97 Other oxidoreductases

1.98 Enzymes using H₂ as reductant (deleted subclass)

1.99 Other enzymes using O₂ as oxidant (deleted subclass)

2.1 Transferring one-carbon groups

2.2 Transferring aldehyde or ketonic groups

2.3 Acyltransferases

2.4 Glycosyltransferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.6 Transferring nitrogenous groups

2.7 Transferring phosphorus-containing groups

2.8 Transferring sulfur-containing groups

2.9 Transferring selenium-containing groups

2.10 Transferring molybdenum- or tungsten-containing groups

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Release 2023.1 (January 2023)