EC Explorer
[browse EC tree] - [search]
EC 1.8.4.13 Details
show Brenda entryEC number
1.8.4.13
Accepted name
L-methionine (S)-S-oxide reductase
Reaction
L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin
Other name(s)
fSMsr,
methyl sulfoxide reductase I and II,
acetylmethionine sulfoxide reductase,
methionine sulfoxide reductase,
L-methionine:oxidized-thioredoxin S-oxidoreductase,
methionine-S-oxide reductase,
free-methionine (S)-S-oxide reductase
Systematic name
L-methionine:thioredoxin-disulfide S-oxidoreductase
Comment
Requires NADPH [2]. The reaction occurs in the opposite direction to that given above. Dithiothreitol can replace reduced thioredoxin. L-Methionine (R)-S-oxide is not a substrate [see EC 1.8.4.14, L-methionine (R)-S-oxide reductase].
History
created 1984 as EC 1.8.4.5, part transferred 2006 to EC 1.8.4.13
back to topEC Tree
1 Oxidoreductases
1.1.1 With NAD+ or NADP+ as acceptor
1.1.3.1 created 1961, deleted 1984 1.1.3.25 created 1986, deleted 2005 1.1.3.26 created 1989, deleted 2002 1.1.3.31 created 1992, deleted 2003 1.1.3.32 created 1999, deleted 2002 1.1.3.33 created 1999, deleted 2002 1.1.3.34 created 1999, deleted 2002 1.1.3.35 created 1999, deleted 2002 1.1.3.36 created 1999, deleted 2002
