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EC 1.1.98.3 Details
EC number
1.1.98.3
Accepted name
decaprenylphospho-β-D-ribofuranose 2-dehydrogenase
Reaction
trans,octacis-decaprenylphospho-β-D-ribofuranose + FAD = trans,octacis-decaprenylphospho-β-D-erythro-pentofuranosid-2-ulose + FADH2
Other name(s)
decaprenylphosphoryl-β-D-ribofuranose 2′-epimerase,
Rv3790,
DprE1,
decaprenylphospho-β-D-ribofuranose 2-oxidase
Systematic name
trans,octacis-decaprenylphospho-β-D-ribofuranose:FAD 2-oxidoreductase
Comment
The enzyme, isolated from the bacterium Mycobacterium smegmatis, is involved, along with EC 1.1.1.333, decaprenylphospho-D-erythro-pentofuranosid-2-ulose 2-reductase, in the epimerization of trans,octacis-decaprenylphospho-β-D-ribofuranose to trans,octacis-decaprenylphospho-β-D-arabinofuranose, the arabinosyl donor for the biosynthesis of mycobacterial cell wall arabinan polymers.
History
created 2012, modified 2014
EC Tree
1.1.5.1 created 1983, deleted 2002