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EC 3.6.1.73 Details
EC number
3.6.1.73
Accepted name
inosine/xanthosine triphosphatase
Reaction
(1) inosine 5′-triphosphate + H2O = inosine 5′-diphosphate + phosphate;;(2) xanthosine 5′-triphosphate + H2O = xanthosine 5′-diphosphate + phosphate
Other name(s)
yjjX (gene name)
Systematic name
inosine/xanthosine 5′-triphosphate phosphohydrolase
Comment
The enzyme, characterized from the bacterium Escherichia coli, preferentially hydrolyses inosine triphosphate and xanthosine triphosphate, which are formed by oxidative deamination damage. By hydrolysing these damaged nucleotides, the enzyme prevents their incorporation into RNA.
History
created 2020
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EC Tree
1 Oxidoreductases
2 Transferases
2.1 Transferring one-carbon groups
2.2 Transferring aldehyde or ketonic groups
2.3 Acyltransferases
2.4 Glycosyltransferases
2.5 Transferring alkyl or aryl groups, other than methyl groups
2.6 Transferring nitrogenous groups
2.7 Transferring phosphorus-containing groups
2.8 Transferring sulfur-containing groups
2.9 Transferring selenium-containing groups
2.10 Transferring molybdenum- or tungsten-containing groups
3 Hydrolases
3.1 Acting on ester bonds
3.2 Glycosylases
3.3 Acting on ether bonds
3.4 Acting on peptide bonds (peptidases)
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.6 Acting on acid anhydrides
3.6.1 In phosphorus-containing anhydrides
3.6.1.1 inorganic diphosphatase
3.6.1.2 trimetaphosphatase
3.6.1.3 adenosinetriphosphatase
3.6.1.4 created 1961, deleted 1965
3.6.1.5 apyrase
3.6.1.6 nucleoside diphosphate phosphatase
3.6.1.7 acylphosphatase
3.6.1.8 ATP diphosphatase
3.6.1.9 nucleotide diphosphatase
3.6.1.10 endopolyphosphatase
3.6.1.11 exopolyphosphatase
3.6.1.12 dCTP diphosphatase
3.6.1.13 ADP-ribose diphosphatase
3.6.1.14 adenosine-tetraphosphatase
3.6.1.15 nucleoside-triphosphate phosphatase
3.6.1.16 CDP-glycerol diphosphatase
3.6.1.17 bis(5′-nucleosyl)-tetraphosphatase (asymmetrical)
3.6.1.18 FAD diphosphatase
3.6.1.19 nucleoside-triphosphate diphosphatase
3.6.1.20 5′-acylphosphoadenosine hydrolase
3.6.1.21 ADP-sugar diphosphatase
3.6.1.22 NAD+ diphosphatase
3.6.1.23 dUTP diphosphatase
3.6.1.24 nucleoside phosphoacylhydrolase
3.6.1.25 triphosphatase
3.6.1.26 CDP-diacylglycerol diphosphatase
3.6.1.27 undecaprenyl-diphosphate phosphatase
3.6.1.28 thiamine-triphosphatase
3.6.1.29 bis(5′-adenosyl)-triphosphatase
3.6.1.30 m7G(5′)pppN diphosphatase
3.6.1.31 phosphoribosyl-ATP diphosphatase
3.6.1.32 created 1984, deleted 2000
3.6.1.33 created 1984, deleted 2000
3.6.1.34 created 1984, deleted 2000
3.6.1.35 created 1984, deleted 2000
3.6.1.36 created 1984, deleted 2000
3.6.1.37 created 1984, deleted 2000
3.6.1.38 created 1984, deleted 2000
3.6.1.39 thymidine-triphosphatase
3.6.1.40 guanosine-5′-triphosphate,3′-diphosphate phosphatase
3.6.1.41 bis(5′-nucleosyl)-tetraphosphatase (symmetrical)
3.6.1.42 guanosine-diphosphatase
3.6.1.43 dolichyldiphosphatase
3.6.1.44 oligosaccharide-diphosphodolichol diphosphatase
3.6.1.45 UDP-sugar diphosphatase
3.6.1.46 created 2000, deleted 2003
3.6.1.47 created 2000, deleted 2003
3.6.1.48 created 2000, deleted 200
3.6.1.49 created 2000, deleted 2003
3.6.1.50 created 2000, deleted 2003
3.6.1.51 created 2000, deleted 2003
3.6.1.52 diphosphoinositol-polyphosphate diphosphatase
3.6.1.53 Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase
3.6.1.54 UDP-2,3-diacylglucosamine diphosphatase
3.6.1.55 8-oxo-dGTP diphosphatase
3.6.1.56 2-hydroxy-dATP diphosphatase
3.6.1.57 UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose hydrolase
3.6.1.58 8-oxo-dGDP phosphatase
3.6.1.59 5′-(N7-methyl 5′-triphosphoguanosine)-[mRNA] diphosphatase
3.6.1.60 diadenosine hexaphosphate hydrolase (AMP-forming)
3.6.1.61 diadenosine hexaphosphate hydrolase (ATP-forming)
3.6.1.62 5′-(N7-methylguanosine 5′-triphospho)-[mRNA] hydrolase
3.6.1.63 α-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase
3.6.1.64 inosine diphosphate phosphatase
3.6.1.65 (d)CTP diphosphatase
3.6.1.66 XTP/dITP diphosphatase
3.6.1.67 dihydroneopterin triphosphate diphosphatase
3.6.1.68 geranyl diphosphate phosphohydrolase
3.6.1.69 8-oxo-(d)GTP phosphatase
3.6.1.70 guanosine-5′-diphospho-5′-[DNA] diphosphatase
3.6.1.71 adenosine-5′-diphospho-5′-[DNA] diphosphatase
3.6.1.72 DNA-3′-diphospho-5′-guanosine diphosphatase
3.6.1.73 inosine/xanthosine triphosphatase
3.6.1.74 mRNA 5′-phosphatase
3.6.1.75 diacylglycerol diphosphate phosphatase
3.6.2 In sulfonyl-containing anhydrides
3.6.3 Acting on acid anhydrides to catalyse transmembrane movement of substances
3.6.3.1 phospholipid-translocating ATPase
3.6.3.2 Mg2+-importing ATPase
3.6.3.3 Cd2+-exporting ATPase
3.6.3.4 Cu2+-exporting ATPase
3.6.3.5 Zn2+-exporting ATPase
3.6.3.6 H+-exporting ATPase
3.6.3.7 Na+-exporting ATPase
3.6.3.8 Ca2+-transporting ATPase
3.6.3.9 Na+/K+-exchanging ATPase
3.6.3.10 H+/K+-exchanging ATPase
3.6.3.11 Cl--transporting ATPase
3.6.3.12 K+-transporting ATPase
3.6.3.13 created 2000, deleted 2001
3.6.3.14 H+-transporting two-sector ATPase
3.6.3.15 Na+-transporting two-sector ATPase
3.6.3.16 arsenite-transporting ATPase
3.6.3.17 monosaccharide-transporting ATPase
3.6.3.18 oligosaccharide-transporting ATPase
3.6.3.19 maltose-transporting ATPase
3.6.3.20 glycerol-3-phosphate-transporting ATPase
3.6.3.21 polar-amino-acid-transporting ATPase
3.6.3.22 nonpolar-amino-acid-transporting ATPase
3.6.3.23 oligopeptide-transporting ATPase
3.6.3.24 nickel-transporting ATPase
3.6.3.25 sulfate-transporting ATPase
3.6.3.26 nitrate-transporting ATPase
3.6.3.27 phosphate-transporting ATPase
3.6.3.28 phosphonate-transporting ATPase
3.6.3.29 molybdate-transporting ATPase
3.6.3.30 Fe3+-transporting ATPase
3.6.3.31 polyamine-transporting ATPase
3.6.3.32 quaternary-amine-transporting ATPase
3.6.3.33 vitamin B12-transporting ATPase
3.6.3.34 iron-chelate-transporting ATPase
3.6.3.35 manganese-transporting ATPase
3.6.3.36 taurine-transporting ATPase
3.6.3.37 guanine-transporting ATPase
3.6.3.38 capsular-polysaccharide-transporting ATPase
3.6.3.39 lipopolysaccharide-transporting ATPase
3.6.3.40 teichoic-acid-transporting ATPase
3.6.3.41 heme-transporting ATPase
3.6.3.42 β-glucan-transporting ATPase
3.6.3.43 peptide-transporting ATPase
3.6.3.44 xenobiotic-transporting ATPase
3.6.3.45 steroid-transporting ATPase
3.6.3.46 cadmium-transporting ATPase
3.6.3.47 fatty-acyl-CoA-transporting ATPase
3.6.3.48 α-factor-transporting ATPase
3.6.3.49 channel-conductance-controlling ATPase
3.6.3.50 protein-secreting ATPase
3.6.3.51 mitochondrial protein-transporting ATPase
3.6.3.52 chloroplast protein-transporting ATPase
3.6.3.53 Ag+-exporting ATPase
3.6.3.54 Cu+-exporting ATPase
3.6.3.55 tungstate-importing ATPase
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.5 Acting on GTP to facilitate cellular and subcellular movement
3.7 Acting on carbon-carbon bonds
3.8 Acting on halide bonds
3.9 Acting on phosphorus-nitrogen bonds
3.10 Acting on sulfur-nitrogen bonds
3.11 Acting on carbon-phosphorus bonds
3.12 Acting on sulfur-sulfur bonds
3.13 Acting on carbon-sulfur bonds
4 Lyases
5 Isomerases
6 Ligases
7 Translocases